重组人IL-4 Rα厂家直销

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专业生产销*(代"售")重组人IL-4 Rα厂家直销，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组人IL-4 Rα厂家直销
产地：国产|进口
规格：10μg|50μg|500μg|1mg
编号：JN1638
品牌：百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met26-His232 在C端含有His标签。

IL-4 Rα质量控制：＞95%(还原性SDS-PAGE)

IL-4 Rα制剂：冻干品

IL-4 Rα保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IL-4 Rα复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IL-4 Rα：
Interleukin 4 Receptor alpha (IL4-Ra) is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family. Mature human IL4-Ra consists of a 207 amino acid (aa) extracellular domain (ECD) that contains a cytokine binding region and one fibronectin type III domain, a 24 aa transmembrane segment, and a 569 aa cytoplasmic domain that contains one Box 1 motif and one ITIM motif. IL4-Ra plays an important role in Th2-biased immune responses, alternative macrophage activation, mucosal immunity, allergic inflammation, tumor progression, and atherogenesis. Soluble forms of IL4-Ra, generated by alternate splicing or proteolysis, retain ligand binding properties and inhibit IL-4 bioactivity. IL4-Ra is a component of two distinct receptor complexes and shows species selectivity between human and mouse. It can associate with the common gamma chain (γc) to form the IL-4 responsive type I receptor in which γc increases the affinity for IL-4 and enables signaling. It can alternatively associate with IL13-Ra1 to form the type II receptor which is responsive to both IL-4 and IL-13. The use of shared receptor components contributes to the overlapping biological effects of IL-4 and IL-13 as well as other cytokines that utilize γc. ~~

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重组人IL-4 Rα厂家直销关键词：JN1638,重组IL-4 Rα,百奥莱博,Recombinant Human Interleukin-4 Receptor Subunit A,重组人IL-4 Rα蛋白


·重组人BOC
编号：JN1320
英文名称：Recombinant Human Brother of CDO
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp31-Ser157在C端含有His标签。

BOC质量控制：＞95%(还原性SDS-PAGE)

BOC制剂：冻干品

BOC保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

BOC复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于BOC：
Brother of CDO is a protein that in humans is encoded by the BOC gene. CDON and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail.


重组人IL-4 Rα厂家直销关键词：JN1638,重组IL-4 Rα,百奥莱博,Recombinant Human Interleukin-4 Receptor Subunit A,重组人IL-4 Rα蛋白


·重组人半胱*酸双加氧酶1(CDO1)
编号：JN0863
英文名称：Recombinant Human Cysteine Dioxygenase Type 1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Asn200在N端含有His标签。

CDO1质量控制：＞95%(还原性SDS-PAGE)

CDO1制剂：液体

CDO1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于CDO1：
Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyzes the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic concentration of intracellular free cysteine within a proper narrow range. CDO1 is able to alter intracellular cysteine levels and glutathione levels.

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