重组人Serpin G1(丝氨酸蛋白酶抑制剂G1) 重组蛋白

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人Serpin G1(丝*酸蛋白酶抑制剂G1) 重组蛋白在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人Serpin G1(丝*酸蛋白酶抑制剂G1) 重组蛋白
品牌：百奥莱博
英文名：Recombinant Human Serine Protease Inhibitor-clade G1
产地：国产|进口
规格：10μg|50μg|500μg|1mg
编号：JN1707
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asn23-Ala500在C端含有His标签。

Serpin G1质量控制：＞95%(还原性SDS-PAGE)

Serpin G1制剂：冻干品

Serpin G1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Serpin G1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Serpin G1：
The Human Serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein. It is the largest member among the serpin class of proteins. Remarkably, Serpin G1 has a 2-domain structure, unlike most family members. The C-terminal serpin domain is similar to other serpins, and this part of Serpin G1 provides the inhibitory activity. The N-terminal domain is not essential for Serpin G1 to inhibit proteinases and has no similarity to other proteins. The main function of Serpin G1 is the inhibition of the complement system to prevent spontaneous activation. Serpin G1 is an acute phase protein and circulates in blood at levels of around 0.25g/L, whose levels rise 2-fold during inflammation. Although named after its complement inhibitory activity, Serpin G1 also inhibits proteinases of the fibrinolytic, clotting, and kinin pathways. Most notably, Serpin G1 play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. It is also the most important physiological inhibitor of fXIIa, chymotrypsin and plasma kallikrein.

更多有关重组人Serpin G1(丝*酸蛋白酶抑制剂G1) 重组蛋白的价格及使用说明等，请联*(代"系")我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：

·重组人*黏蛋白(*粘附素)(Cadherin-3)(CDH3)
编号：JN0785
英文名称：Recombinant Human Cadherin-3
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu25-Gly654在C端含有His标签。

Cadherin-3/CDH3质量控制：＞95%(还原性SDS-PAGE)

Cadherin-3/CDH3制剂：冻干品

Cadherin-3/CDH3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Cadherin-3/CDH3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Cadherin-3/CDH3：
Cadherin-3 (CDH3) is a single-pass type I membrane protein that belongs to the cadherin superfamily. CDH3 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. CDH3 is expressed in some normal epithelial tissues and in some carcinoma cell lines. CDH3 preferentially interacts with themselves in a homophilic manner in connecting cells. CDH3 is involved in loss of heterozygosity events in breast and prostate cancer. Mutations in CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.


重组人Serpin G1(丝*酸蛋白酶抑制剂G1) 重组蛋白关键词：重组人Serpin G1蛋白,JN1707,重组人丝*酸蛋白酶抑制剂G1,重组Serpin G1


·重组小鼠IFN-gamma R1(CD119)(C端带Fc标签)
编号：JN1412
英文名称：Recombinant Mouse Interferon gamma Receptor 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ala26-Asp253在C端带有Fc标签。

IFN-gamma R1/CD119质量控制：＞95%(还原性SDS-PAGE)

IFN-gamma R1/CD119制剂：冻干品

IFN-gamma R1/CD119保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IFN-gamma R1/CD119复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IFN-gamma R1/CD119：
The tetrameric receptor complex for IFNγ consists of two subunits, IFNGR1 (IFNγ Rα) and IFNGR2 (IFNγ Rβ), through which the dimeric IFN-γ exerts its biological functions, including antiviral, antiproliferation and immune-modulatory activity in mammals. Both IFNGR1 and IFNGR2 are single transmembrane proteins belonging to the class II cytokine family. FNGR1, widely expressed in most host cells, is essential for IFNγ binding, receptor trafficking, and signal transduction. IFNGR1 possesses an intracellular Janus tyrosine kinase (JAK) 1 binding site, a signal transducer and activator of transcription 1 (STAT1) binding site. The resulting STAT1 homodimers translocate from the cytoplasm to the nucleus and bind to the interferon-gamma activated sequence (GAS) promoter to induce expression of downstream interferon stimulated genes (ISGs).


重组人Serpin G1(丝*酸蛋白酶抑制剂G1) 重组蛋白关键词：重组人Serpin G1蛋白,JN1707,重组人丝*酸蛋白酶抑制剂G1,重组Serpin G1


·重组小鼠TNFRSF1A
编号：JN0466
英文名称：Recombinant Mouse Tumor Necrosis Factor Receptor I
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ile22-Ala212表达纯化得来。

TNFRSF1A质量控制：＞95%(还原性SDS-PAGE)

TNFRSF1A制剂：冻干品

TNFRSF1A保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TNFRSF1A复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TNFRSF1A：
Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the human genetic disorder called tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome

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