重组人雌激素受体α 重组蛋白

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖重组人雌激素受体α 重组蛋白在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：重组人雌激素受体α 重组蛋白
编号：JN0857
产地：国产|进口
品牌：百奥莱博
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Gln116在N端含有His标签。

Estrogen Receptor质量控制：＞95%(还原性SDS-PAGE)

Estrogen Receptor制剂：冻干品

Estrogen Receptor保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Estrogen Receptor复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Estrogen Receptor：
Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5 UTRs and use different promoters.

除重组人雌激素受体α 重组蛋白外，我公司正在打折促销以下产品：

·重组人生长阻滞和DNA损伤诱导45β(GADD45B)
编号：JN0887
英文名称：Recombinant Human Growth Arrest and DNA Damage-Inducible Protein GADD45 beta
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Arg160在N端含有His标签。

GADD45B质量控制：＞95%(还原性SDS-PAGE)

GADD45B制剂：冻干品

GADD45B保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

GADD45B复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于GADD45B：
Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of growth and apoptosis. GADD45B reacts to environmental stresses by mediating activation of stress-responsive MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. In addition, GADD45B participates in the down-regulation of hepatocellular carcinoma (HCC). It may serve as a possible therapeutic target.


重组人雌激素受体α 重组蛋白关键词：重组雌激素受体α,重组人雌激素受体α蛋白,JN0857,百奥莱博,Recombinant Human Estrogen receptor alpha


·重组人精子IZUMO4蛋白
编号：JN1165
英文名称：Recombinant Human Izumo sperm-egg fusion protein 4
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的His16-His214在C端带有Fc标签。

IZUMO4质量控制：＞95%(还原性SDS-PAGE)

IZUMO4制剂：冻干品

IZUMO4保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

IZUMO4复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于IZUMO4：
Izumo sperm-egg fusion protein 4 is a sperm membrane protein which plays a key role in the fusion in the mouse. IZUMO4 has an N-terminal domain with significant homology to the N-terminal domain of Izumo.It belongs to the Izumo family . Izumo 4 is a soluble protein expressed in the testis and in other tissues. Izumo domain possesses the ability to form dimers, whereas the transmembrane domain or the cytoplasmic domain or both of Izumo 1 are required for the formation of multimers of higher order.


重组人雌激素受体α 重组蛋白关键词：重组雌激素受体α,重组人雌激素受体α蛋白,JN0857,百奥莱博,Recombinant Human Estrogen receptor alpha


·重组人Importinβ1(KPNB1)(核转运受体蛋白)(输入蛋白β1)
编号：JN1588
英文名称：Recombinant Human Importin Subunit Beta-1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Ala876在N端含有His标签。

KPNB1质量控制：＞95%(还原性SDS-PAGE)

KPNB1制剂：液体

KPNB1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于KPNB1：
Importin subunit beta-1(KPNB1) is a member of the importin beta family. KPNB1 contains 1 importin N-terminal domain and 19 HEAT repeats. It is involved in nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. Its functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. The import of proteins containing a classical nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits. Each of these subunits is part of the karyopherin family of proteins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta do*(代"c")ks the complex at the cytoplasmic side of the nuclear pore complex. It mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5.

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