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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
常温
- 保质期:
1年
- 英文名:
UNC3866
- 库存:
10000
- 供应商:
南京赛泓瑞
- CAS号:
1872382-47-2
- 规格:
330.246913580247
产品名称:UNC3866
UNC3866生物活性:
| UNC3866 is a potent antagonist of the CBX7-H3 interaction as determined by AlphaScreen (IC50=66±1.2 nM) and is more than 100-fold selective for CBX7 over the other nine members of this methyl-lysine (Kme) reader panel. |
UNC3866制备储备液:
| 浓度溶解体积质量 | 1mg | 5mg | 10mg |
| 1mM | 2.1032mL | 10.5159mL | 21.0318mL |
| 5mM | 0.4206mL | 2.1032mL | 4.2064mL |
| 10mM | 0.2103mL | 1.0516mL | 2.1032mL |
| 50mM | 0.0421mL | 0.2103mL | 0.4206mL |
UNC3866临床数据( 数据源于:http:// clinicaltrials.gov)
Conversion of different model animals based on BSA(Value based on data from FDA Draft Guidelines)
Animal A (mg/kg)=Animal B(mg/kg)multiplied by AnimalBm系数/AnimalAm系数
For example, to modify the dose of resveratrol uesd for a mouse(22.4mg/kg) to a dose based on the BSA for a rat, multiply 22.4mg/kg by the Km factor for a mouse and zhen divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2mg/kg
南京赛泓瑞生物科技有限公司是专业从事生化试剂、分子生物学试剂、实验耗材及实验仪器研发、销售、服务为一体的专业性生物科技公司。本着服务科学的理念,赛泓瑞建立了生命科学研究工具的研发、生产、销售及技术服务平台,现已有数万余种产品,并每年不断开发新产品,为广大的生命科学研究人员、医学、药学、农业、环保等的科研人员提供科研工具性产品及技术服务.
经营范围:抑制剂、ELISA试剂盒、原代细胞和细胞株、化学试剂、蛋白、抗体、分子试剂和试剂盒。
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文献和实验Improved Vectors for Selection of Transgenic Caenorhabditis elegans
the identification of transgenic animals within a background of non-transformed animals, the unc-119 gene is often used as a visible marker as the unc-119 mutants are small and move poorly and the larger size and smoother movement of rescued animals make them clearly
10.9 Nature:揭示蛋白 BORIS 是耐药性癌症产生的罪魁祸首
Catalyze 13 -Hydrolyzation of Gibberellins ③ Nature:揭示蛋白 UNC93B1 抑制 TLR7 信号转导和阻止自身免疫反应机制在一项新的研究中,来自美国加州大学伯克利分校的研究人员报道了 Toll 样受体(TLR)运输分子伴侣 UNC93B1 的一种新功能:它特异性地限制 TLR7 但不限制 TLR9 的信号转导,并阻止小鼠中的 TLR7 依赖性的自身免疫反应。这些研究人员发现 UNC93B1 中的突变导致增强的 TLR7 信号转导,同时也破坏了与蛋白
Biolistic Transformation of Caenorhabditis elegans
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