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- 文献和实验
- 技术资料
- 保存条件:
常温
- 保质期:
1年
- 英文名:
Cyclophosphamide monohydrate
- 库存:
10000
- 供应商:
南京赛泓瑞
- CAS号:
6055-19-2
- 规格:
166.666666666667
产品名称:Cyclophosphamide monohydrate
Cyclophosphamide monohydrate生物活性:
| Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. |
Cyclophosphamide monohydrate制备储备液:
| 浓度溶解体积质量 | 1mg | 5mg | 10mg |
| 1mM | 2.1032mL | 10.5159mL | 21.0318mL |
| 5mM | 0.4206mL | 2.1032mL | 4.2064mL |
| 10mM | 0.2103mL | 1.0516mL | 2.1032mL |
| 50mM | 0.0421mL | 0.2103mL | 0.4206mL |
Cyclophosphamide monohydrate临床数据( 数据源于:http:// clinicaltrials.gov)
Conversion of different model animals based on BSA(Value based on data from FDA Draft Guidelines)
Animal A (mg/kg)=Animal B(mg/kg)multiplied by AnimalBm系数/AnimalAm系数
For example, to modify the dose of resveratrol uesd for a mouse(22.4mg/kg) to a dose based on the BSA for a rat, multiply 22.4mg/kg by the Km factor for a mouse and zhen divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2mg/kg
南京赛泓瑞生物科技有限公司是专业从事生化试剂、分子生物学试剂、实验耗材及实验仪器研发、销售、服务为一体的专业性生物科技公司。本着服务科学的理念,赛泓瑞建立了生命科学研究工具的研发、生产、销售及技术服务平台,现已有数万余种产品,并每年不断开发新产品,为广大的生命科学研究人员、医学、药学、农业、环保等的科研人员提供科研工具性产品及技术服务.
经营范围:抑制剂、ELISA试剂盒、原代细胞和细胞株、化学试剂、蛋白、抗体、分子试剂和试剂盒。
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文献和实验Treatment of SCCVII Tumors with Systemic Chemotherapy and Interleukin-12 Gene Therapy Combination
Cyclophosphamide and Interleukin-12 (IL-12) have been successfully used in clinical trials for treating malignancies. In this study, we explore the coadministration of cyclophosphamide and IL-12 plasmid DNA followed by electroporation
的使用,耐受性相当良好,不良反应非常少见,副作用则是对视网膜的毒性,所以应定期做眼科的检查。 Cyclophosphamide:高剂量静脉注射疗法广泛应用在治疗狼疮病。副作用如恶心、呕吐、掉发、骨髓毒性、卵巢衰竭、无精虫症、及出血性膀胱炎等。 Azothioprine:一般认为疗效比 Cyclophosphamide 小,毒性也较小。
The In Vitro Mammalian Chromosome Aberration Test
of asymmetrical structural chromosome aberrations is measured. Human peripheral blood lymphocytes do not normally divide. The assessment of the effects of cyclophosphamide on lymphocytes, stimulated to divide in whole blood cultures in vitro, is described
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