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T.pallidum TmpA

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  • $150 - 1200
  • prospecbio
  • TRP-250
  • 以色列
  • 2025年07月12日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      大量

    • 英文名

      Treponema pallidum TmpA Recombinant

    • 保质期

      1年

    • 供应商

      上海沪震实业有限公司

    • 保存条件

      -20°C

    • 规格

      100µg/500µg/1000µg

    T.pallidum TmpA

    CATALOGUE NUMBER

    TRP-250

    INTRODUCTION

    Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue.

    DESCRIPTION

    The E.Coli derived recombinant protein contains the T.Pallidum TmpA immunodominant regions. The protein contains beta- galactosidase (114 kDa) fused at the N- terminus.

    SOURCE

    Escherichia Coli.

    PURIFICATION METHOD

    Treponema Pallidum protein was purified by proprietary chromatographic technique.

    PURITY

    Treponema Pallidum protein is >90% pure as determined by 10% PAGE (coomassie staining).

    FORMULATION

    8M urea, 20mM Tris-HCl pH-8 & 10mM B-ME.

    STABILITY

    Treponema Pallidum protein although stable at 4°C for 1 week, should be stored below -18°C. 
    Please prevent freeze thaw cycles.

    SPECIFICITY

    Immunoreactive with sera of T.Pallidum infected individuals.

    APPLICATIONS

    Treponema Pallidum protein binds to murine anti-TmpA protein monoclonal antibodies and Treponema pallidum converted human serum polyclonal antibodies in ELISA and Western Elisa. Dot Blots and Lateral Flow immunochromatographic diagnostics test.

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
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    • Protocol for the Detection of Treponema pallidum in Paraffin-Embedded Specimens

      describes detailed procedures for nucleic acid extraction and PCR detection of Treponema pallidum using FFPE tissue.

    • Protocols for Detection and Typing of Treponema pallidum Using PCR Methods

      in later stages. Taking swab samples from these ulcerative lesions gives the best options for detection by PCR of T. palillidum . Alternatively blood samples can be analyzed in later stages. If tested positive in screening PCR assays, T. pallidum

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