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- PRO-2271
- 以色列
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 英文名：
Streptococcus Pyogenes Arginine Transketolase Recombinant
- 保质期：
1年
- 供应商：
上海沪震实业有限公司
- 保存条件：
-20°C
- 规格：
50μg/100μg/1mg
CATALOGUE NUMBER
PRO-2271
INTRODUCTION
Streptococcus pyogenes is the cause of many significant human diseases, ranging from mild superficial skin infections to life-threatening systemic diseases. Infections usually begin in the throat or skin. The most conspicuous sign is a strawberry-like rash. Instances of mild S. pyogenes infections include pharyngitis (strep throat) and localized skin infection (impetigo). The invasion of S. pyogenes and its multiplication in the fascia can lead to necrotizing fasciitis, a life-threatening condition requiring surgery. Throat infections linked with the release of certain toxins lead to scarlet fever. Other toxigenic S. pyogenes infections may lead to potentially life-threatening streptococcal toxic shock syndrome. S. pyogenes may also cause disease in the form of post-infectious "nonpyogenic" (not associated with local bacterial multiplication and pus formation) syndromes. These autoimmune-mediated complications develop from a small percentage of infections and comprise rheumatic fever and acute post infectious glomerulonephritis. Acute glomerulonephritis (inflammation of the renal glomerulus) can arise from streptococcal pharyngitis or skin infection. The Streptococcus pyogenes bacterium is acutely sensitive to penicillin, even though certain strains have developed resistance to macrolides, tetracyclines, and clindamycin.DESCRIPTION
Recombinant Streptococcus Pyogenes Arginine Transketolase produced in E.coli is a non-glycosylated, polypeptide chain having a calculated molecular mass of 78,837 Dalton.S.Pyogenes tkt is expressed with a 10xHis tag at N-terminus and purified by proprietary chromatographic techniques.
SOURCE
Escherichia Coli.PHYSICAL APPEARANCE
Sterile Filtered clear solution.FORMULATION
S.Pyogenes tkt is supplied in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol.STABILITY
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Avoid multiple freeze-thaw cycles.
PURITY
Greater than 80.0% as determined by SDS-PAGE.IMMUNOLOGICAL FUNCTIONS
1. Binds IgG- and IgM- and IgA-type human antibodies.2. Immunodot test with positive/negative sera panels.
USAGE
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Proteomic Analysis of Proteins Secreted by Streptococcus pyogenes
Streptococcus pyogenes secretes various proteins to the extracellular environment. During infection, these proteins interact with human macromolecules and contribute to pathogenesis. We describe a proteomic approach routinely used
Murine Model of Cutaneous Infection with Streptococcus pyogenes
Despite the medical advances achieved during the last century to fight against bacteria, viruses, fungi and parasites, infectious diseases are still a major cause of death, disability, and social and economic upheaval for millions
S－腺苷甲硫氨酸 S－ adenosylmethionine 亦称活性甲硫氨酸，在生物体内由 ATP与甲硫氨酸在甲硫氨酸活化酶的作用下合成。甲硫键是高能键，另外其丙基胺部分也加入到多胺化合物中。当胆碱、肌酸及其它甲基化合物生成时它作为甲基供体而起作用。认为甲硫氨酸的分解也经过此物质。
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