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- 2025年12月18日
- WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
- 详见说明书
- 详见说明书
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- 抗体名：
B淋巴细胞白血病前体蛋白转录因子1抗体
- 抗体英文名：
Anti-PBX1
- 靶点：
详见说明书
- 浓度：
1mg/1ml
- 应用范围：
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
- 宿主：
详见说明书
- 供应商：
上海一研
- 库存：
29
- 级别：
详见说明书
- 目录编号：
详见说明书
- 抗原来源：
Rabbit
- 保质期：
详见说明书
- 适应物种：
详见说明书
- 标记物：
详见说明书
- 克隆性：
多克隆
- 保存条件：
Store at -20 °C
- 形态：
详见说明书
- 亚型：
IgG
- 免疫原：
KLH conjugated synthetic peptide derived from Human PBX1
- 规格：
0.2ml/200μg
B淋巴细胞白血病前体蛋白转录因子1抗体图片储存温度：
存在于血清、组织培养上清液或腹水中的抗体在-20℃下能够长期储存。低温存放不会损伤抗体活性。抗体的工作液通常储存于4℃中。此温度下，抗体的活性能稳定数月至数年亦不损失。抗体溶液不应反复冻融，因为反复冻融将导致部分抗体失活并产生不需要的蛋白—蛋白凝聚物。抗体的凝聚能导致活性丧失。这是由于抗原结合位点的空间构象被破坏，或由于产生的不溶物被离心或过滤而除去。冷凝蛋白类的抗体不能存放于4℃。因为在4℃下此类抗体会发生沉淀。一些鼠源性IgG3亚类的抗体有此特性。如果抗体在4℃下发生沉淀，就应该存放于室温下的叠氮钠溶液中。
B淋巴细胞白血病前体蛋白转录因子1抗体图片按理化性质和生物学功能，可将其分为IgM、IgG、IgA、IgE、IgD五类。
公司所有产品低价促销，更有惊喜等你拿，超值好产品，预定B淋巴细胞白血病前体蛋白转录因子1抗体图片即送好礼。好货提前订，快递更给力。产品质量好，到货快，质量三包。
英文名称 Anti-PBX1
中文名称 B淋巴细胞白血病前体蛋白转录因子1抗体图片
别 名 DKFZp686B09108; Homeo box protein PBX1; Homeo box protein PRL; Homeobox protein PBX 1; Homeobox protein PBX1; Homeobox protein PRL; MGC126627; PBX 1; Pbx1; PBX1_HUMAN; Pre B cell leukemia homeobox 1; Pre B cell leukemia transcription factor 1; Pre-B-cell leukemia transcription factor 1; PRL.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Zebrafish
产品类型 一抗
研究领域 细胞生物 发育生物学 信号转导 干细胞 转录调节因子 淋巴细胞 t-淋巴细胞 b-淋巴细胞 表观遗传学
蛋白分子量 predicted molecular weight: 47kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from Human PBX1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
Function : Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation.
Subunit : Forms a heterodimer with MEIS1 which binds DNA including a cAMP-responsive sequence in CYP17. Also forms heterotrimers with MEIS1 and a number of HOX proteins including HOXA9, HOXD4, HOXD9 and HOXD10. Interacts with PBXIP1 and TLX1. Isoform PBX1a interacts with MEIS2 isoform 4, SP1, SP3 and KLF4. Isoform PBX1b is part of a PDX1:PBX1b:MEIS2b complex; PBX1b recruits Meis2B to the complex.
Subcellular Location : Nucleus.
Tissue Specificity : Expressed in all tissues except in cells of the B and T lineage.
DISEASE : Note=A chromosomal aberration involving PBX1 is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Translocation t(1;19)(q23;p13.3) with TCF3. E2A-PBX1 transforms cells by constitutively activating transcription of genes regulated by PBX1 or by other members of the PBX protein family.
Similarity : Belongs to the TALE/PBX homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links : UniProtKB/Swiss-Prot:
IgM抗体是免疫应答中首先分泌的抗体。它们在与抗原结合后启动补体的级联反应。它们还把入侵者相互连接起来，聚成一堆便于巨噬细胞的吞噬；
IgG抗体激活补体，中和多种毒素。IgG持续的时间长，是唯一能在母亲妊娠期穿过胎盘保护胎儿的抗体。他们还从乳腺分泌进入初乳，使新生儿得 到保护；
IgA抗体进入身体的黏 膜表面，包括呼吸、消化、生殖等管道的黏膜，中和感染因子。还可以通过母乳的初乳把这种抗体输送到新生儿的消化道黏膜中，是在母乳中含量最多，最为重要的一类抗体；
IgE抗体的尾部与嗜碱细胞、肥大细胞的细胞膜结合。当抗体与抗原结合后，嗜碱细胞与肥大细胞释放组织胺一类物质促进炎症的发展。这也是引发速发型过敏反应的抗体；
IgD抗体的作用还不太清楚。它们主要出现在成熟的B淋巴细胞表面上，可能与B细胞的分化有关。（IgD于1995年从人骨髓瘤蛋白中发现，分子量为175kD，主要由扁桃体、脾等处浆细胞产生，人血清中IgD浓度为3～40μg/ml,不到血清总Ig的1%，在个体发育中合成较晚。IgD铰链区很长，且对蛋白酶水解敏感，因此IgD半衰期很短，仅2.8天。血清中IgD确切的免疫功能尚不清楚。在B细胞分化到成熟B细胞阶段，除了表达SmIgD，抗原刺激后表现为免疫耐受。成熟B细胞活化后或者活化后或者变成记忆B细胞时，SmIgD逐渐消失。
B淋巴细胞白血病前体蛋白转录因子1抗体图片的分类：
按作用对象，可将其分为抗毒素、抗菌抗体、抗病毒抗体和亲细胞抗体（能与细胞结合的免疫球蛋白，如1型变态反应中的lgE反应素抗体，能吸附在靶细胞膜上）；按理化性质和生物学功能，可将其分为IgM、IgG、IgA、IgE、IgD五类；按抗体的来源，可 将其分为天然抗体和免疫抗体。抗体就是免疫球蛋白，是改变了的球蛋白分子。由特异性抗原刺激产生，抗体的产生是由于抗原侵入人体后引起各种免疫细胞相互作用，使淋巴细胞中的B细胞分化增殖而形成浆细胞，浆细胞可产生分泌抗体。
RabbitAnti-humanIgM/AlexaFluor555AlexaFluor555标记的兔抗人IgM规格:0.1ml
FGFR4/CD334成纤维细胞生因子受体4抗体规格:0.1ml
CDCA2细胞分裂周期蛋白2抗体规格:0.2ml
CyclinL/CCNL1周期素L抗体规格:0.2ml
Phospho-Rictor(Thr1135)磷酸化雷帕霉素靶蛋白复合体2抗体规格:0.1ml
Laminin2alpha层粘蛋白α2抗体规格:0.2ml
XRCC3X射线修复交叉互补蛋白3抗体规格:0.2ml
phospho-CDK7(Thr170)磷酸化周期素依赖性激酶7抗体规格:0.1ml
ZDHHC17/HIP14NFκB激活蛋白205抗体规格:0.1ml
Phospho-HER4(Tyr984)磷酸化HER4抗体规格:0.1ml
Amphiphysin神经元突触前膜蛋白抗体规格:0.2ml
Plectin网蛋白抗体规格:0.2ml
PCDH11X原钙粘附蛋白11X抗体规格:0.2ml[Gln9]-Amyloid β-Protein (1-40) Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gln-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
[Nle253]-HSV-1 UL 26 Open Reading Frame (238-257) Gly-Ile-Ala-Gly-His-Thr-Tyr-Leu-Gln-Ala-Ser-Glu-Lys-Phe-Lys-Nle-Trp-Gly-Ala-Glu
[Trp4]-Kemptide Leu-Arg-Arg-Trp-Ser-Leu-Gly
[Val5] Angiotensin II, human Asp-Arg-Val-Tyr-Val-His-Pro-Phe
Ac-Glutamine Ac-Gln
ADR1-derived peptide Leu-Lys-Lys-Leu-Thr-Arg-Arg-Ala-Ser-Phe-Ser-Gly-Gln
B淋巴细胞白血病前体蛋白转录因子1抗体图片Amyloid β-Protein (6-20) His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe
Atrial Natriuretic Factor (3-28) (human) Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge Cys5-Cys21 )
Biotin-Galanin, human Biotin-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser
BQ-3020 Ac-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp
Calmodulin-Dependent Protein Kinase II (290-309) Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Al
Cholecystokinin-33 (10-20) (bovine, porcine) Ile-Lys-Asn-Leu-Gln-Ser-Leu-Asp-Pro-Ser-His
DAGO Tyr-D-Ala-Gly-N-Me-Phe-Gly-OL
Eglin c (60-63)-methyl ester Thr-Asn-Val-Val-Ome
存在于血清、组织培养上清液或腹水中的抗体在-20℃下能够长期储存。低温存放不会损伤抗体活性。抗体的工作液通常储存于4℃中。此温度下，抗体的活性能稳定数月至数年亦不损失。抗体溶液不应反复冻融，因为反复冻融将导致部分抗体失活并产生不需要的蛋白—蛋白凝聚物。抗体的凝聚能导致活性丧失。这是由于抗原结合位点的空间构象被破坏，或由于产生的不溶物被离心或过滤而除去。冷凝蛋白类的抗体不能存放于4℃。因为在4℃下此类抗体会发生沉淀。一些鼠源性IgG3亚类的抗体有此特性。如果抗体在4℃下发生沉淀，就应该存放于室温下的叠氮钠溶液中。
B淋巴细胞白血病前体蛋白转录因子1抗体图片按理化性质和生物学功能，可将其分为IgM、IgG、IgA、IgE、IgD五类。
公司所有产品低价促销，更有惊喜等你拿，超值好产品，预定B淋巴细胞白血病前体蛋白转录因子1抗体图片即送好礼。好货提前订，快递更给力。产品质量好，到货快，质量三包。
英文名称 Anti-PBX1
中文名称 B淋巴细胞白血病前体蛋白转录因子1抗体图片
别 名 DKFZp686B09108; Homeo box protein PBX1; Homeo box protein PRL; Homeobox protein PBX 1; Homeobox protein PBX1; Homeobox protein PRL; MGC126627; PBX 1; Pbx1; PBX1_HUMAN; Pre B cell leukemia homeobox 1; Pre B cell leukemia transcription factor 1; Pre-B-cell leukemia transcription factor 1; PRL.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Zebrafish
产品类型 一抗
研究领域 细胞生物 发育生物学 信号转导 干细胞 转录调节因子 淋巴细胞 t-淋巴细胞 b-淋巴细胞 表观遗传学
蛋白分子量 predicted molecular weight: 47kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from Human PBX1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
Function : Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation.
Subunit : Forms a heterodimer with MEIS1 which binds DNA including a cAMP-responsive sequence in CYP17. Also forms heterotrimers with MEIS1 and a number of HOX proteins including HOXA9, HOXD4, HOXD9 and HOXD10. Interacts with PBXIP1 and TLX1. Isoform PBX1a interacts with MEIS2 isoform 4, SP1, SP3 and KLF4. Isoform PBX1b is part of a PDX1:PBX1b:MEIS2b complex; PBX1b recruits Meis2B to the complex.
Subcellular Location : Nucleus.
Tissue Specificity : Expressed in all tissues except in cells of the B and T lineage.
DISEASE : Note=A chromosomal aberration involving PBX1 is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Translocation t(1;19)(q23;p13.3) with TCF3. E2A-PBX1 transforms cells by constitutively activating transcription of genes regulated by PBX1 or by other members of the PBX protein family.
Similarity : Belongs to the TALE/PBX homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links : UniProtKB/Swiss-Prot:
IgM抗体是免疫应答中首先分泌的抗体。它们在与抗原结合后启动补体的级联反应。它们还把入侵者相互连接起来，聚成一堆便于巨噬细胞的吞噬；
IgG抗体激活补体，中和多种毒素。IgG持续的时间长，是唯一能在母亲妊娠期穿过胎盘保护胎儿的抗体。他们还从乳腺分泌进入初乳，使新生儿得 到保护；
IgA抗体进入身体的黏 膜表面，包括呼吸、消化、生殖等管道的黏膜，中和感染因子。还可以通过母乳的初乳把这种抗体输送到新生儿的消化道黏膜中，是在母乳中含量最多，最为重要的一类抗体；
IgE抗体的尾部与嗜碱细胞、肥大细胞的细胞膜结合。当抗体与抗原结合后，嗜碱细胞与肥大细胞释放组织胺一类物质促进炎症的发展。这也是引发速发型过敏反应的抗体；
IgD抗体的作用还不太清楚。它们主要出现在成熟的B淋巴细胞表面上，可能与B细胞的分化有关。（IgD于1995年从人骨髓瘤蛋白中发现，分子量为175kD，主要由扁桃体、脾等处浆细胞产生，人血清中IgD浓度为3～40μg/ml,不到血清总Ig的1%，在个体发育中合成较晚。IgD铰链区很长，且对蛋白酶水解敏感，因此IgD半衰期很短，仅2.8天。血清中IgD确切的免疫功能尚不清楚。在B细胞分化到成熟B细胞阶段，除了表达SmIgD，抗原刺激后表现为免疫耐受。成熟B细胞活化后或者活化后或者变成记忆B细胞时，SmIgD逐渐消失。
B淋巴细胞白血病前体蛋白转录因子1抗体图片的分类：
按作用对象，可将其分为抗毒素、抗菌抗体、抗病毒抗体和亲细胞抗体（能与细胞结合的免疫球蛋白，如1型变态反应中的lgE反应素抗体，能吸附在靶细胞膜上）；按理化性质和生物学功能，可将其分为IgM、IgG、IgA、IgE、IgD五类；按抗体的来源，可 将其分为天然抗体和免疫抗体。抗体就是免疫球蛋白，是改变了的球蛋白分子。由特异性抗原刺激产生，抗体的产生是由于抗原侵入人体后引起各种免疫细胞相互作用，使淋巴细胞中的B细胞分化增殖而形成浆细胞，浆细胞可产生分泌抗体。
RabbitAnti-humanIgM/AlexaFluor555AlexaFluor555标记的兔抗人IgM规格:0.1ml
FGFR4/CD334成纤维细胞生因子受体4抗体规格:0.1ml
CDCA2细胞分裂周期蛋白2抗体规格:0.2ml
CyclinL/CCNL1周期素L抗体规格:0.2ml
Phospho-Rictor(Thr1135)磷酸化雷帕霉素靶蛋白复合体2抗体规格:0.1ml
Laminin2alpha层粘蛋白α2抗体规格:0.2ml
XRCC3X射线修复交叉互补蛋白3抗体规格:0.2ml
phospho-CDK7(Thr170)磷酸化周期素依赖性激酶7抗体规格:0.1ml
ZDHHC17/HIP14NFκB激活蛋白205抗体规格:0.1ml
Phospho-HER4(Tyr984)磷酸化HER4抗体规格:0.1ml
Amphiphysin神经元突触前膜蛋白抗体规格:0.2ml
Plectin网蛋白抗体规格:0.2ml
PCDH11X原钙粘附蛋白11X抗体规格:0.2ml[Gln9]-Amyloid β-Protein (1-40) Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gln-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
[Nle253]-HSV-1 UL 26 Open Reading Frame (238-257) Gly-Ile-Ala-Gly-His-Thr-Tyr-Leu-Gln-Ala-Ser-Glu-Lys-Phe-Lys-Nle-Trp-Gly-Ala-Glu
[Trp4]-Kemptide Leu-Arg-Arg-Trp-Ser-Leu-Gly
[Val5] Angiotensin II, human Asp-Arg-Val-Tyr-Val-His-Pro-Phe
Ac-Glutamine Ac-Gln
ADR1-derived peptide Leu-Lys-Lys-Leu-Thr-Arg-Arg-Ala-Ser-Phe-Ser-Gly-Gln
B淋巴细胞白血病前体蛋白转录因子1抗体图片Amyloid β-Protein (6-20) His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe
Atrial Natriuretic Factor (3-28) (human) Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge Cys5-Cys21 )
Biotin-Galanin, human Biotin-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Val-Gly-Asn-His-Arg-Ser-Phe-Ser-Asp-Lys-Asn-Gly-Leu-Thr-Ser
BQ-3020 Ac-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp
Calmodulin-Dependent Protein Kinase II (290-309) Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Al
Cholecystokinin-33 (10-20) (bovine, porcine) Ile-Lys-Asn-Leu-Gln-Ser-Leu-Asp-Pro-Ser-His
DAGO Tyr-D-Ala-Gly-N-Me-Phe-Gly-OL
Eglin c (60-63)-methyl ester Thr-Asn-Val-Val-Ome
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机制。为了初步了解MM和CLL的生物学基础，我们整合了10个共有风险位点的染色体捕获、组蛋白标记和转录因子结合的调控数据。有趣的是，我们在这些位点上发现了与B细胞发育、基因组稳定性和其他癌症发生有关的基因。这支持了这一原则，即这些区域可以影响两种疾病的发展，特别是当MM和CLL起源于同一个细胞在不同成熟阶段。在未来，我们的目标是在生物学环境中研究GWAS的发现，提供体内外相互作用基因和调控机制的证据。最终，我们的遗传密码支持我们观察到的更高的生物学，从细胞行为到发育和疾病。由于生殖系遗传学在概念上被设定
进口分装 F00123 转录因子 AP-1(AP-1) ELISA 48T/96T 2000/3000 进口分装 F00124 人 Apelin(Apelin) ELISA 48T/96T 2000/3000 进口分装 F00125 增殖诱导配体 (APRIL) ELISA 48T/96T 2000/3000 进口分装 F00126 水通道蛋白 -4(AQP-4) ELISA 48T/96T 2000/3000 进口分装 F00151 骨碱性磷酸酶 (BALP
点分散。结果表明同样一种通用因子GR(包 括SPI、OCT等)结合于多个位置的顺式元件上就可诱导转录活性。 （1）通用因子的调控机制 多种细胞中普遍存在的“通用因子”具有特异性的原因在于不同细胞中转录因子的有效浓度或与顺式元件的亲合力不周； 作为诱导性和细胞专一性表达的介导因子NFkB在表达k链的B细胞质中游离存在并可进入细胞核内；而在其它细胞质中与抑制因子IkB形成复合体。佛波酯(TPA)等诱导IkB的磷酸化可促使复合体的解离，NFkB即成为活化形式，使其在细胞核内达到足够的有效浓度。此外，果蝇
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B淋巴细胞白血病前体蛋白转录因子1抗体图片
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