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- 2025年11月11日
- WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 详见说明书
- 详见说明书
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- 详细信息
- 技术资料
- 抗体名：
磷酸化转录因子RelB蛋白抗体
- 抗体英文名：
Anti-phospho-RelB(Ser551)
- 靶点：
详见说明书
- 浓度：
1mg/1ml
- 应用范围：
WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
- 宿主：
详见说明书
- 供应商：
上海一研
- 库存：
43
- 级别：
详见说明书
- 目录编号：
详见说明书
- 抗原来源：
Rabbit
- 保质期：
详见说明书
- 适应物种：
详见说明书
- 标记物：
详见说明书
- 克隆性：
多克隆
- 保存条件：
Store at -20 °C
- 形态：
详见说明书
- 亚型：
IgG
- 免疫原：
KLH conjugated Synthesised phosphopeptide derived from human RelB around the phosphorylation site of Ser551
- 规格：
0.2ml/200μg
公司抗体应用于WB、IHC、IF、ELISA等实验中，磷酸化转录因子RelB蛋白抗体品牌品质保证，提供完善的售前、售中、售后服务！欢迎来电咨询或联系在线客服！我们将竭诚为您服务！
英文名称 Anti-phospho-RelB(Ser551)
中文名称 磷酸化转录因子RelB蛋白抗体品牌
别 名 RELB (phospho S551); RelB (phospho Ser551); RelB (Ser551); I REL; IREL; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; RelB; Reticuloendotheliosis viral oncogene homolog B; Transcription factor RelB; v rel avian reticuloendotheliosis viral oncogene homolog; v rel reticuloendotheliosis viral oncogene homolog B; RELB_HUMAN; I-Rel.
浓 度 1mg/1ml
规 格 0.1ml/100μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Cow, Rabbit
产品类型 一抗 磷酸化抗体
研究领域 肿瘤 免疫学 信号转导 转录调节因子
蛋白分子量 predicted molecular weight: 64kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human RelB around the phosphorylation site of Ser551
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The NFKB complex consists of NFKB1 or NFKB2 bound to REL, RELA, or RELB. The NFKB complex is inhibited by I kappa B proteins (NFKBIA, or NFKBIB), which inactivate NF kappa B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I kappa B proteins by kinases (IKBKA, or IKBKB,) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B complex.
Function : NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. RELB neither associates with DNA nor with RELA/p65 or REL. Stimulates promoter activity in the presence of NFKB2/p49. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
Subunit : Component of the NF-kappa-B RelB-p50 complex. Component of the NF-kappa-B RelB-p52 complex. Self-associates; the interaction seems to be transient and may prevent degradation allowing for heterodimer formation with p50 or p52. Interacts with NFKB1/p50, NFKB2/p52 and NFKB2/p100. Interacts with NFKBID.
Subcellular Location : Nucleus. Cytoplasm, cytoskeleton, centrosome. Note=Co-localizes with NEK6 in the centrosome.
Post-translational modifications : Phosphorylation at 'Thr-103' and 'Ser-573' is followed by proteasomal degradation.
Similarity : Contains 1 RHD (Rel-like) domain.
Database links : UniProtKB/Swiss-Prot: Q
磷酸化转录因子RelB蛋白抗体品牌具有高度的特异性，免疫组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来，以此作为抗原或半抗原，通过免疫动物后获得特异性的抗体，再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的，因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来，以其达到对组织或细胞中的未知抗原进行定性，定位或定量的研究。
磷酸化转录因子RelB蛋白抗体品牌包括以下几个步骤：
1、制备抗原。
2、选择实验动物。
3、动物免疫。
4、试取血进行测试，看看是否成功免疫。
5、如果成功免疫，杀死实验动物，采集全部血清。
6、纯化出抗体。
7、鉴定抗体。包括纯度以及特异性。
磷酸化转录因子RelB蛋白抗体品牌的功能
抗体的主要功能是与抗原（包括外来的和自身的）相结合，从而有效地清除侵入机体内的微生物、寄生虫等异物，抗体（antibody）是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活，也可能无效但有时也会对机体造成病理性损害，如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生，对人体可造成危害。
磷酸化转录因子RelB蛋白抗体品牌的优点：
①耐热、耐酸、耐碱、抗有机溶剂以及金属离子，稳定性好，室温下可以长期保存；
②制备简单，操作方便，可以进行批量；
③不必免疫动物，且可获得免疫动物所不能得到的“抗体”；
④可以反复使用；
⑤价格低廉。因此，设计、合成既具有类似生物抗体的高亲合性和高专一性，又具有耐热、耐酸、耐碱且又可以长期稳定的人工抗体，在部分领域替代生物抗体以进行仿生分子识别，或者完成一些生物抗体所不能完成的工作，具有重要的科学意义，在化学、生命科学和环境科学等方面具有广阔的应用前景
公司专业供应各种进口、国产一抗及二抗，品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌，品种多达7000多种，由于产品的数量众多，产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。
SCN1ASCN1A抗体规格:0.1ml
Thioredoxin2线粒体硫氧还蛋白2抗体规格:0.1ml
phospho-TPH(Ser260)磷酸化色氨酸羟化酶抗体规格:0.1ml
CLCA4钙激活氯离子通道4抗体规格:0.1ml
Sema3CSema3C蛋白抗体规格:0.2ml
Nectin3/CD113细胞粘附分子3抗体（脊髓灰质炎病毒受体相关蛋白3）规格:0.1ml
CXorf56X染色体开放阅读框56抗体规格:0.2ml
phospho-RAD51(Tyr315)磷酸化Rad51抗体规格:0.1ml
Sidekick1细胞粘附分子伴侣蛋白1抗体规格:0.2ml
VIPReceptor1/VAPC1管活性肠肽受体-1抗体0.1ml
CK12/Cytokeratin12细胞角蛋白12抗体0.2ml
AQP5水通道蛋白5抗体规格:0.1ml
CGRP/CGRP2CGRP降钙素基因相关肽抗体规格:0.1ml
Gentamicin(3G7)庆大霉素单克隆抗体规格:0.2mlMagainin 2 Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser
MMP-1 Substrate I, fluorogenic Dnp-Pro-Leu-Ala-Leu-Trp-Ala-Arg
Neuropeptide Y (13-36) (porcine) Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
Ovalbumin(257-264) antigen peptide Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu
Parathyroid Hormone (1-34), human Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe
Prepro- Atrial Natriuretic Factor (104-116), human Ser-Ser-Asp-Arg-Ser-Ala-Leu-Leu-Lys-Ser-Lys-Leu-Arg
PT-141 Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys Asp-Lys
Scyliorhinin II, amide ,dogfish Ser-Pro-Ser-Asn-Ser-Lys-Cys-Pro-Asp-Gly-Pro-Asp-Cys-Phe-Val-Gly-Leu-Met-NH2 (Disulfide bridge: Cys7-Cys13 )
磷酸化转录因子RelB蛋白抗体品牌Substance P (1-7) Arg-Pro-Lys-Pro-Gln-Gln-Phe
Tyr-ACTH (4-9) Tyr-Met-Glu-His-Phe-Arg-Trp
WWamide-1 Trp-Lys-Glu-Met-Ser-Val-Trp-NH2
β- Amyloid (4-10) Phe-Arg-His-Asp-Ser-Gly-Tyr
β-Defensin-4, human Glu-Leu-Asp-Arg-Ile-Cys-Gly-Tyr-Gly-Thr-Ala-Arg-Cys-Arg-Lys-Lys-Cys-Arg-Ser-Gln-Glu-Tyr-Arg-Ile-Gly-Arg-Cys-Pro-Asn-Thr-Tyr-Ala-Cys-Cys-Leu-Arg-Lys (Disulfide bridge: Cys6-Cys33, Cys13-Cys27, Cys17-Cys34)
[Asp5,6,Me-Phe8] Substance P Asp-Asp-Phe-Me-Phe-Gly-Leu-Met-NH2
[Des-Gly77,His78] Myelin Basic Protein (68-84), bovine Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ala-Gln-Arg-Pro-Gln-Asp-Glu-Asn
[Fmoc-Glu70,Ala71,72,Lys74]-C3a (70-77) Fmoc-Glu-Ala-Ala-Leu-Lys-Leu-Ala-Arg
英文名称 Anti-phospho-RelB(Ser551)
中文名称 磷酸化转录因子RelB蛋白抗体品牌
别 名 RELB (phospho S551); RelB (phospho Ser551); RelB (Ser551); I REL; IREL; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; RelB; Reticuloendotheliosis viral oncogene homolog B; Transcription factor RelB; v rel avian reticuloendotheliosis viral oncogene homolog; v rel reticuloendotheliosis viral oncogene homolog B; RELB_HUMAN; I-Rel.
浓 度 1mg/1ml
规 格 0.1ml/100μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Cow, Rabbit
产品类型 一抗 磷酸化抗体
研究领域 肿瘤 免疫学 信号转导 转录调节因子
蛋白分子量 predicted molecular weight: 64kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human RelB around the phosphorylation site of Ser551
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The NFKB complex consists of NFKB1 or NFKB2 bound to REL, RELA, or RELB. The NFKB complex is inhibited by I kappa B proteins (NFKBIA, or NFKBIB), which inactivate NF kappa B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I kappa B proteins by kinases (IKBKA, or IKBKB,) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B complex.
Function : NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. RELB neither associates with DNA nor with RELA/p65 or REL. Stimulates promoter activity in the presence of NFKB2/p49. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
Subunit : Component of the NF-kappa-B RelB-p50 complex. Component of the NF-kappa-B RelB-p52 complex. Self-associates; the interaction seems to be transient and may prevent degradation allowing for heterodimer formation with p50 or p52. Interacts with NFKB1/p50, NFKB2/p52 and NFKB2/p100. Interacts with NFKBID.
Subcellular Location : Nucleus. Cytoplasm, cytoskeleton, centrosome. Note=Co-localizes with NEK6 in the centrosome.
Post-translational modifications : Phosphorylation at 'Thr-103' and 'Ser-573' is followed by proteasomal degradation.
Similarity : Contains 1 RHD (Rel-like) domain.
Database links : UniProtKB/Swiss-Prot: Q
磷酸化转录因子RelB蛋白抗体品牌具有高度的特异性，免疫组织化学正是利用了这一原理。先将组织或细胞中的某种化学物质提取出来，以此作为抗原或半抗原，通过免疫动物后获得特异性的抗体，再以此抗体去探测组织或细胞中的同类的抗原物质。由于抗原与抗体的复合物是无色的，因此还必须借助于组织化学的方法将抗原抗体结合的部位显示出来，以其达到对组织或细胞中的未知抗原进行定性，定位或定量的研究。
磷酸化转录因子RelB蛋白抗体品牌包括以下几个步骤：
1、制备抗原。
2、选择实验动物。
3、动物免疫。
4、试取血进行测试，看看是否成功免疫。
5、如果成功免疫，杀死实验动物，采集全部血清。
6、纯化出抗体。
7、鉴定抗体。包括纯度以及特异性。
磷酸化转录因子RelB蛋白抗体品牌的功能
抗体的主要功能是与抗原（包括外来的和自身的）相结合，从而有效地清除侵入机体内的微生物、寄生虫等异物，抗体（antibody）是一种应答抗原产生的、可与抗原特异性结合的蛋白质。每种抗体与特定的抗原决定基结合。这种结合可以使抗原失活，也可能无效但有时也会对机体造成病理性损害，如抗核抗体、抗双链DNA抗体、抗甲状腺球蛋白抗体等一些自身抗体的产生，对人体可造成危害。
磷酸化转录因子RelB蛋白抗体品牌的优点：
①耐热、耐酸、耐碱、抗有机溶剂以及金属离子，稳定性好，室温下可以长期保存；
②制备简单，操作方便，可以进行批量；
③不必免疫动物，且可获得免疫动物所不能得到的“抗体”；
④可以反复使用；
⑤价格低廉。因此，设计、合成既具有类似生物抗体的高亲合性和高专一性，又具有耐热、耐酸、耐碱且又可以长期稳定的人工抗体，在部分领域替代生物抗体以进行仿生分子识别，或者完成一些生物抗体所不能完成的工作，具有重要的科学意义，在化学、生命科学和环境科学等方面具有广阔的应用前景
公司专业供应各种进口、国产一抗及二抗，品牌有R&D、Santa Cruz、Bipec、Millipore等国际知名品牌，品种多达7000多种，由于产品的数量众多，产品的宿主、抗原来源及应用范围(WB、IH(F/P)、FC、ELISA、IP、IF等)有所不同。
SCN1ASCN1A抗体规格:0.1ml
Thioredoxin2线粒体硫氧还蛋白2抗体规格:0.1ml
phospho-TPH(Ser260)磷酸化色氨酸羟化酶抗体规格:0.1ml
CLCA4钙激活氯离子通道4抗体规格:0.1ml
Sema3CSema3C蛋白抗体规格:0.2ml
Nectin3/CD113细胞粘附分子3抗体（脊髓灰质炎病毒受体相关蛋白3）规格:0.1ml
CXorf56X染色体开放阅读框56抗体规格:0.2ml
phospho-RAD51(Tyr315)磷酸化Rad51抗体规格:0.1ml
Sidekick1细胞粘附分子伴侣蛋白1抗体规格:0.2ml
VIPReceptor1/VAPC1管活性肠肽受体-1抗体0.1ml
CK12/Cytokeratin12细胞角蛋白12抗体0.2ml
AQP5水通道蛋白5抗体规格:0.1ml
CGRP/CGRP2CGRP降钙素基因相关肽抗体规格:0.1ml
Gentamicin(3G7)庆大霉素单克隆抗体规格:0.2mlMagainin 2 Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser
MMP-1 Substrate I, fluorogenic Dnp-Pro-Leu-Ala-Leu-Trp-Ala-Arg
Neuropeptide Y (13-36) (porcine) Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
Ovalbumin(257-264) antigen peptide Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu
Parathyroid Hormone (1-34), human Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe
Prepro- Atrial Natriuretic Factor (104-116), human Ser-Ser-Asp-Arg-Ser-Ala-Leu-Leu-Lys-Ser-Lys-Leu-Arg
PT-141 Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys Asp-Lys
Scyliorhinin II, amide ,dogfish Ser-Pro-Ser-Asn-Ser-Lys-Cys-Pro-Asp-Gly-Pro-Asp-Cys-Phe-Val-Gly-Leu-Met-NH2 (Disulfide bridge: Cys7-Cys13 )
磷酸化转录因子RelB蛋白抗体品牌Substance P (1-7) Arg-Pro-Lys-Pro-Gln-Gln-Phe
Tyr-ACTH (4-9) Tyr-Met-Glu-His-Phe-Arg-Trp
WWamide-1 Trp-Lys-Glu-Met-Ser-Val-Trp-NH2
β- Amyloid (4-10) Phe-Arg-His-Asp-Ser-Gly-Tyr
β-Defensin-4, human Glu-Leu-Asp-Arg-Ile-Cys-Gly-Tyr-Gly-Thr-Ala-Arg-Cys-Arg-Lys-Lys-Cys-Arg-Ser-Gln-Glu-Tyr-Arg-Ile-Gly-Arg-Cys-Pro-Asn-Thr-Tyr-Ala-Cys-Cys-Leu-Arg-Lys (Disulfide bridge: Cys6-Cys33, Cys13-Cys27, Cys17-Cys34)
[Asp5,6,Me-Phe8] Substance P Asp-Asp-Phe-Me-Phe-Gly-Leu-Met-NH2
[Des-Gly77,His78] Myelin Basic Protein (68-84), bovine Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ala-Gln-Arg-Pro-Gln-Asp-Glu-Asn
[Fmoc-Glu70,Ala71,72,Lys74]-C3a (70-77) Fmoc-Glu-Ala-Ala-Leu-Lys-Leu-Ala-Arg
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