产品概述:Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
简单描述:Goat Polyclonal MKP-1 / DUSP1 Antibody (C-Terminus). Validated for use in WB, IHC-P, E.
详情:FunctionDual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.Cellular_LocationNucleus.Tissue_LocationExpressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney