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- 详细信息
- 文献和实验
- 技术资料
- 库存:
50
- 供应商:
信裕生物
- 英文名:
Human Ceruloplasmin
- 规格:
100ug/500ug/1mg
Product Description
Human Ceruloplasmin
Human Ceruloplasmin is a ferroxidase enzyme that, in humans, is encoded by the CP gene. It is the major copper-carrying protein in the blood. Human CER is an enzyme synthesized in the liver containing 8 atoms of copper in its structure. Although it is often considered a copper transport protein, this is not its primary function, just as human hemoglobin is not a carrier of iron, although it contains iron. The main carrier for copper in the plasma of humans is albumin. Human Ceruloplasmin enzyme (ferroxidase) catalyzes the oxidation of ferrous iron (Fe2) to ferric iron (Fe3), therefore assisting in Human Ceruloplasmin enzyme transport in the plasma in association with transferrin, which can only carry iron in the ferric state.
This product is for in vitro research use only, is not to be consumed by animals or humans, and should be handled with general precaution as if capable of spreading infectious disease.
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文献和实验铜蓝蛋白(ceruloplasmin,CER)是一种含铜的α2 糖蛋白,分子量约为12万-16万,不易纯化。目前所知为一个单链多肽,每分子含6-7个铜原子,由于含铜而呈蓝色,含糖约10%,末端唾液酸与多肽链连接,具有遗传上的基因多形性。 CER具有氧化酶的活性,对多酚及多胺类底物有催化其氧化的能力。最近研究认为CER可催化Fe2 氧化为Fe3 。对于CER是否是铜的载体存在不同看法。血清中铜的含量虽有95%以非扩散状态处于CER,而有5%呈可透析状态由肠管
Ceruloplasmin Detection by SDS-PAGE, Immunoblotting, and In Situ Oxidase Activity
Ceruloplasmin is an acute-phase reactant that functions as a ferroxidase, oxidizing Fe++ to Fe+++ , the latter being able to combine with apotransferrin to form transferrin, the primary iron transport protein in the plasma. Ferroxidases
人 Neuritin 酶联免疫分析(ELISA) 试剂盒使用说明书 本试剂仅供研究使用 目的:本试剂盒用于测定人血清,血浆及相关液体样本 中Neuritin 的含量。 实验原理: 本试剂盒应用双抗体夹心法测定标本中人 Neuritin 水平。用纯化的 Neuritin 抗体 包被微孔板,制成固相抗体,往包被单抗的微孔中加入 Neuritin ,再与 HRP 标记的 Neuritin 抗体结合,形成抗体
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