- ¥2260
- ABCAM
- ab170904
- 2025年12月09日
- IHC-FoFr, IHC-P, WB
- Mouse, Rat, Human
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- 详细信息
- 文献和实验
- 技术资料
- 克隆性：
多克隆
- 抗体英文名：
Anti-P Glycoprotein
- 适应物种：
Mouse, Rat, Human
- 应用范围：
IHC-FoFr, IHC-P, WB
- 规格：
40 µl
货号：ab170904
适用于: IHC-FoFr, IHC-P, WB
不适用于: ICC/IF
与反应: Mouse, Rat, Human
P-glycoprotein 1 (also known as Multidrug resistance protein 1) has a predicted molecular weight of 141 kDa, however it has 3 potential glycosylation sites (N-linked) which may affect the migration of the protein. In our hands ab170904 detects a predominant protein band migrating in the region of 180-200 kDa and typically will demonstrate a smear on the membrane in the region of the 150 – 300 kDa due to the glycosylation profile of the protein. It may be necessary to optimise your cell or tissue lysis protocol to efficiently extract P-glycoprotein 1 as it is a multi-pass membrane protein. Abcam recommends not boiling the sample after lysis. Please note that we do not recommend this antibody for use in IHC-P on mouse or rat tissue
文献：
- Seaman S et al. Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature. Cancer Cell 31:501-515.e8 (2017). Read more (PubMed: 28399408) »
- Zhang C et al. Growth of tyrosine kinase inhibitor-resistant Philadelphia-positive acute lymphoblastic leukemia: Role of bone marrow stromal cells. Oncol Lett 13:2059-2070 (2017). WB . Read more (PubMed: 28454362) »
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