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- 详细信息
- 文献和实验
- 技术资料
- 库存：
大量
- 英文名：
Rat IL-10 ELISA Kit
- 保质期：
1年
- 供应商：
上海钰博生物科技有限公司
- 保存条件：
-2-8℃
- 规格：
盒
Rat IL-10 ELISA Kit
Product Description
Rat IL-10 ELISA Kit
Our Rat IL-10 ELISA Kit is a sandwich ELISA intended for the quantitative determination of rat IL-10 in cell culture supernates, serum and plasma (EDTA).
Interleukin-10, also called cytokine synthesis inhibitory factor, is implicated in tumorigenesis, and it has been shown that polymorphisms in its gene promoter correlate with differential amounts of production. IL-10 is an important cytokine with anti-inflammatory, anti-immune, and antifibrotic functions. It is also an important regulatory cytokine whose involvement extends into diverse areas of the human immune system. IL-10 is a recently described natural endogenous immunosuppressive cytokine that has been identified in human, murine, and other organisms. IL-10 significantly affects chemokine biology, because human IL-10 inhibits chemokine production and is a specific chemotactic factor for CD8 T cells. It suppresses the ability of CD4 T cells, but not CD8 T cells, to migrate in response to IL-8. Interleukin-10 gene polymorphisms and interleukin-10 production capability may contribute to the development of skin squamous cell carcinomas after renal transplantation. The interleukin-10 locus contributes to the heritability of psoriasis susceptibility. With regard to sudden infant death, IL-10 is of special interest. This is an immunoregulatory cytokine that plays an important role in the development of infectious disease. The mIL-10 gene is mapped to mouse chromosome 1 and the hIL-10 gene is also mapped to human chromosome 1.
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