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- 详细信息
- 技术资料
- 保存条件:
冷藏
- 保质期:
长期
- 英文名:
Recombinant Mouse Natural killer cell receptor 2B4
- 库存:
323
- 供应商:
北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。
北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括重组小鼠2B4(SLAMF4)(CD244)特价促销在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。
名称:重组小鼠2B4(SLAMF4)(CD244)特价促销
品牌:百奥莱博
编号:JN1633
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Mouse Natural killer cell receptor 2B4
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gln20-Asn221在C端含有His标签。
2B4/SLAMF4/CD244质量控制:>95%(还原性SDS-PAGE)
2B4/SLAMF4/CD244制剂:冻干品
2B4/SLAMF4/CD244保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
2B4/SLAMF4/CD244复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于2B4/SLAMF4/CD244:
Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins have an extracellular domain (ECD) with two or four Ig-like domains and at least two cytoplasmic immunoreceptor tyrosine-based switch motifs (ITSMs). 2B4 interacts with CD48, while other SLAM family proteins interact in a homophilic manner. The mouse 2B4 cDNA encodes a 397 amino acid (aa) precursor that includes a 19 aa signal sequence, a 207 aa ECD with one Ig-like V-type and one C2-type Ig-like domain, a 21 aa transmembrane segment, and a 150 aa cytoplasmic domain with four ITSMs. Within the ECD, mouse 2B4 shares 46% and 68% aa sequence identity with human and rat 2B4, respectively. 2B4/CD48 signaling cooperates with other receptor systems to either promote or inhibit NK and CD8+ T cell activation. The inhibitory activities are distinct from those of MHC I restricted inhibitory NK cell receptors. Ligation of 2B4 with antibodies or CD48 constructs can directly trigger inhibitory signaling or disrupt an inhibitory interaction, leading to cellular activation. 2B4 can also induce signaling through CD48.
欲了解更多重组小鼠2B4(SLAMF4)(CD244)特价促销的品牌、产地、价格及说明书等产品信息,请致电北京百奥莱博科技有限公司,我们将竭诚为您服务,另外,以下产品正在火爆促销:
·重组人ETFB(电子转移黄素蛋白β)
编号:JN1033
英文名称:Recombinant Human Electron transfer flavoprotein subunit beta
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Ile255在N端含有His标签。
ETFB质量控制:>95%(还原性SDS-PAGE)
ETFB制剂:液体
ETFB保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于ETFB:
Electron transfer flavoprotein subunit beta is a subunit of electron transfer flavoprotein, serves as a specific electron acceptor for several dehydrogenases. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Electron transfer flavoprotein subunit beta and alpha combine a heterodimer can binds 1 FAD per dimer. Defects in ETFB are the cause of glutaric aciduria type 2B (GA2B).
重组小鼠2B4(SLAMF4)(CD244)特价促销关键词:重组小鼠2B4,重组小鼠SLAMF4,重组小鼠2B4蛋白,JN1633,重组小鼠CD244
·重组人ECH1
编号:JN1388
英文名称:Recombinant Human Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial
规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Thr34-Leu328在N端含有His标签。
ECH1质量控制:>95%(还原性SDS-PAGE)
ECH1制剂:液体
ECH1保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于ECH1:
Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria.It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway.
重组小鼠2B4(SLAMF4)(CD244)特价促销关键词:重组小鼠2B4,重组小鼠SLAMF4,重组小鼠2B4蛋白,JN1633,重组小鼠CD244
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北京百莱博科技有限公司专业生产分子生物学试剂产品,欢迎来电咨询选购重组小鼠2B4(SLAMF4)(CD244)特价促销。
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