重组人LAG3(淋巴细胞活化基因3蛋白) 分子生物学试剂

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括重组人LAG3(淋巴细胞活化基因3蛋白) 分子生物学试剂在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：重组人LAG3(淋巴细胞活化基因3蛋白) 分子生物学试剂
编号：JN1378
品牌：百奥莱博
英文名：Recombinant Human Lymphocyte Activation Gene 3 Protein
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu23-Gly434在C端含有His标签。

LAG3质量控制：＞95%(还原性SDS-PAGE)

LAG3制剂：冻干品

LAG3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

LAG3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于LAG3：
Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling. It can lead to increased antigen-specific T-cell responses in vivo. LAG-3 has higher affinity to MHC class II than CD4.

除重组人LAG3(淋巴细胞活化基因3蛋白) 分子生物学试剂外，我公司正在打折促销以下产品：

·重组人KIR2DL3
编号：JN1553
英文名称：Recombinant Human Killer Cell Immunoglobulin-like Receptor, Two Domain Long Cytoplasmic Tail, 3
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的His22-His245在C端含有His标签。

KIR2DL3质量控制：＞95%(还原性SDS-PAGE)

KIR2DL3制剂：冻干品

KIR2DL3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

KIR2DL3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于KIR2DL3：
Killer-Cell Immunoglobulin-Like Receptors (KIRs) are important cells of the immune system. KIRs are a family of Natural Killer (NK) Cells surface glycoproteins. KIRs control the killing function of these cells by interacting with MHC class I molecules. This interaction allows KIRs to identify virally infected cells or tumor cells by the distinctive low level of Class I MHC on their surface. The majority of KIRs are inhibitory, their recognition of MHC suppresses the cytotoxic activity of their NK cell. Only a limited number of KIRs have the capacity to activate cells. KIR2DL3 is an inhibitory Killer Cell Ig-like Receptor. KIR2DL3 recognizes class I MHC molecules (HLA-Cw1, -Cw3, -Cw7, and Cw8). KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis.


重组人LAG3(淋巴细胞活化基因3蛋白) 分子生物学试剂关键词：JN1378,重组人LAG3蛋白,重组LAG3,重组人淋巴细胞活化基因3蛋白

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重组人LAG3(淋巴细胞活化基因3蛋白) 分子生物学试剂关键词：JN1378,重组人LAG3蛋白,重组LAG3,重组人淋巴细胞活化基因3蛋白


·重组人蛋白精*酸甲基转移酶1(PRMT1)
编号：JN0950
英文名称：Recombinant Human Protein Arginine N-Methyltransferase 1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Arg343在N端含有His标签。

PRMT1质量控制：＞95%(还原性SDS-PAGE)

PRMT1制剂：液体

PRMT1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于PRMT1：
Protein Arginine N-Methyltransferase 1 (PRMT1) is a cytoplasmic protein that belongs to the protein arginine N-methyltransferase family. PRMT1 is a arginine methyltransferase that functions as a histone methyltransferase for H4. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes. PRMT1 methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. PRMT1 is responsible for the majority of cellular arginine methylation activity. Together with dimethylated PIAS1, it represses STAT1 transcriptional activity in the late phase of interferon gamma (IFN-gamma) signaling. It may be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and serve as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway.

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