重组小鼠DNAM-1(CD226)北京价格

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博主要从事生物试剂的生产和销*(代"售")，产品线涵盖重组小鼠DNAM-1(CD226)北京价格在内的分子生物学试剂产品，还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。

名称：重组小鼠DNAM-1(CD226)北京价格
品牌：百奥莱博
编号：JN1618
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse DNAX Accessory Molecule-1
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu19-Pro254在C端含有His标签。

DNAM-1/CD226质量控制：＞95%(还原性SDS-PAGE)

DNAM-1/CD226制剂：冻干品

DNAM-1/CD226保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

DNAM-1/CD226复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于DNAM-1/CD226：
Mouse DNAX accessory molecule-1(DNAM-1) is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily. As an activating receptor, it interacts with the ligands CD155 and CD112, and activates natural killer (NK) cells via its immu-noreceptor tyrosine-based activatory motif (ITAM). Mature mouse DNAM-1 has extracellular domain (ECD) that contains two Ig-like C2-set domains, and possesses a cytoplasmic region that contains motifs for binding PDZ domains. DNAM-1 is expressed on several lymphoid and myeloid cell types and interacts with CD155/PVR and Nectin-2/CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, induces dendritic cell maturation, initiates megakaryocyte and activated platelet adhesion to vascular endothelial cells, and stimulates monocyte extravasation; Conversely, it inhibits the formation of osteoclasts. Platelet-endothelium interactions that are mediated by DNAM-1 enable the metastasis of tumor cells to the lung.

欲咨询购买重组小鼠DNAM-1(CD226)北京价格，请致电北京百奥莱博科技有限公司，为您提供最全面周到的产品服务，除此之外，我公司正在促销以下产品：
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BTN90802 大提柱式DNA清除剂 Maxi Column DNA Erasol
ARB13258 小鼠嗜酸粒细胞趋化因子(ECF)含量检测 Mouse eosinophil chemotactic factor,ecf ELISA KIT
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Acr-Bis(20%,19.6%:0.4%)   500ml
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ARB12741 小鼠Ⅱ型胶原(Col Ⅱ)elisa检测 Mouse collagen type Ⅱ,col Ⅱ ELISA KIT
50-70-4 D-山梨醇 D-Sorbitol
ARB11212 人细胞色素P450c21A/21-羟化酶(CYP21A)检测服务 Human cytochrome p450c21/21-hydroxylase,cyp21a ELISA KIT
PY02-230  O/F培养基(GLGB)  250克  
BTN101106 沉淀型TMB显色试剂盒 Precipitated TMB Chromogenic Kit
ARB14130 小鼠总胆红素(TB)尿液中含量检测 
2-亚硝基-1-*酚 Ammoninm nickel sulfate 132-53-6
Western转移缓冲液(5×)   500ml
ARB12491 大鼠活化素A受体抗体(ACV-RAb)检测服务 Rat anti-activin a receptor antibody,acv-rab ELISA KIT
BL0958 胶体金标记兔抗豚鼠Ig抗体
重组小鼠DNAM-1(CD226)北京价格关键词：重组小鼠CD226,JN1618,重组小鼠DNAM-1蛋白,重组DNAM-1


·重组人CD33(Siglec-3)
编号：JN1832
英文名称：Recombinant Human Sialic Acid Binding Ig-like Lectin 3
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp18-His259在C端含有Fc标签和His标签

CD33/Siglec-3质量控制：＞95%(还原性SDS-PAGE)

CD33/Siglec-3制剂：冻干品

CD33/Siglec-3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD33/Siglec-3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD33/Siglec-3：
CD33 is a type I Lectin belonging to the Ig superfamily. CD33 contains an N terminal Ig like V type domain, which mediates sialic acid binding, followed by one Ig like C2 type domain, a transmembrane region and a cytoplasmic tail containing two conserved immunoreceptor tyrosine based inhibition motifs (ITIMs). Eleven human Siglecs have been characterized. Siglecs 5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. They are collectively referred to as CD33 related Siglecs. CD33 related Siglecs have differential expression pattern within the hematopoietic system. They are involved in the regulation of cellular activation within the immune system. Siglec 3 expression is restricted to cells of myelomonocytic lineage. Siglec3 recruits SHP1 and SHP2 to its ITIMs upon phosphorylation.


重组小鼠DNAM-1(CD226)北京价格关键词：重组小鼠CD226,JN1618,重组小鼠DNAM-1蛋白,重组DNAM-1


·重组人唾液酸酶1(Sialidase-1)
编号：JN1738
英文名称：Recombinant Human N-acetyl-alpha-Neuraminidase 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu48-Leu415在C端含有His标签。

Sialidase-1质量控制：＞95%(还原性SDS-PAGE)

Sialidase-1制剂：液体

Sialidase-1保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于Sialidase-1：
Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues; it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.

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