Anti-PDX1 Polyclonal Antibody

英文名称Rabbit PDX1 Polyclonal Antibody别名GSF;IDX-1;IPF1;IUF1;MODY4;PAGEN1;PDX-1;STF-1 
应用WB稀释比例WB1:500-1:1000交叉反应Human,Mouse,Rat蛋白分子量31kDaGene ID3651保存Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.储存液PBS with 0.02% sodium azide, 50% glycerol, pH7.3.纯化方法Affinity purification亚型IgG免疫原A synthetic peptide of human PDX1性状Lyophilized or LiquidSwiss ProtP52945克隆类型Polyclonal Antibody来源Rabbit背景资料The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).