- ¥960 - 1600
- 江蓝纯
- K003472P
- 2025年07月12日
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- 详细信息
- 技术资料
- 库存：
99
- 供应商：
江蓝纯
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ¥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ¥1600.0 |
| 英文名称 | Rabbit GNAS Polyclonal Antibody |
|---|---|
| 别名 | CPB;PASP;PCPB |
| 应用 | WB |
| 稀释比例 | WB1:500-1:2000 |
| 交叉反应 | Human,Mouse,Rat |
| 蛋白分子量 | 28kDa |
| Gene ID | 2778 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human GNAS |
| 性状 | Lyophilized or Liquid |
| Swiss Prot | O95467,P63092,P84996,Q5JWF2 |
| 克隆类型 | Polyclonal Antibody |
| 来源 | Rabbit |
| 背景资料 | This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly found in imprinted genes and correlates with transcript expression. An antisense transcript is produced from an overlapping locus on the opposite strand. One of the transcripts produced from this locus, and the antisense transcript, are paternally expressed noncoding RNAs, and may regulate imprinting in this region. In addition, one of the transcripts contains a second overlapping ORF, which encodes a structurally unrelated protein - Alex. Alternative splicing of downstream exons is also observed, which results in different forms of the stimulatory G-protein alpha subunit, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene result in pseudohypoparathyroidism type 1a, pseudohypoparathyroidism type 1b, Albright hereditary osteodystrophy, pseudopseudohypoparathyroidism, McCune-Albright syndrome, progressive osseus heteroplasia, polyostotic fibrous dysplasia of bone, and some pituitary tumors. |
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Anti-GNAS Polyclonal Antibody
¥960 - 1600
