Anti-β-Arrestin 1 Monoclonal A

英文名称Mouse β-Arrestin 1 Monoclonal Antibody别名β-Arrestin 1应用WB稀释比例WB1:500交叉反应Human蛋白分子量51KDaGene ID408保存Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.储存液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 69% Glycerol.纯化方法Affinity purification亚型IgG2b免疫原Recombinant human β-Arrestin 1 protein.性状Lyophilized or LiquidSwiss ProtP49407克隆号6A1-D7-C9克隆类型Monoclonal Antibody来源Mouse背景资料Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011].