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Recombinant Mouse OX40 Ligand/

TNFSF4/OX40L
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  • ¥1170 - 24640
  • 江蓝纯
  • P00216
  • 2025年07月14日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      99

    • 供应商

      江蓝纯

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1170.0
    规格:50ug产品价格:¥3520.0
    规格:500ug产品价格:¥17240.0
    规格:1mg产品价格:¥24640.0
    Known as Tumor necrosis factor ligand superfamily member 4; OX40 ligand; OX40L; CD252; Tnfsf4
    Derived from Human Cells
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    Shipping The product is shipped at ambient temperature.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Endotoxin Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
    Background OX40 ligand (OX40L), also called CD252, is a single-pass type II membrane protein of the TNF/TNF receptor superfamily. OX40L is expressed by DCs, macrophages and B cells and signals via its cognate receptor OX40 which is mainly expressed on APCs. OX40L/OX40 interactions are important in T-cell activation and survival and for the generation of memory T cells from activated effector T cells. OX40L–OX40 co-stimulation leads to activation of TNF receptor associated factor (TRAF) 2, 3 and 5. This pathway has been shown to prolong the survival of effector CD4+Th cells as well as contributes to generation of memory T cells.

    Recombinant Mouse OX40 Ligand is produced by our Mammalian expression system and the target gene encoding Ser51-Leu198 is expressed with a 8His tag at the N-terminus.

     

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