Anti-Glycoprotein-340 (gp-340)

Anti-Glycoprotein-340 (gp-340)

Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。
官方网站：www.bioporto.com

Cat. No.

HYB 213-062

Product name

Anti-Glycoprotein-340 (gp-340)

Description

Mouse monoclonal antibody

Specificity

HYB 213-06 reacts with gp-340 also known as salivary scavenger and agglutinin.

Immunogen

Native gp-340 purified from bronchoalveolar lavage fluid from patients with pulmonary alveolar proteinosis.

Application

ELISA, WB, IHC

Species reactivity (positive)

Human

Species reactivity (negative)

Not determined

Subclass

IgG1/k

Gene ID

1755

Clone number

1G4

Epitope

Protein chain (1)

Content

Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.

Purification

Protein-A purified

Form

Liquid

Solvent

0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide

Storage

4-8ºC without exposure to light. No precautions necessary during handling.

Target

Glycoprotein (gp)-340 is member of the scavenger receptor superfamily and has been identified as a putative SP-D receptor. Gp-340 has been shown to bind SP-D in a calcium-dependent manner through a protein-protein interaction. Like SP-D, gp-340 is found in the lungs and immunohistochemistry shows high expression in alveolar macrophages. An identical protein, salivary agglutinin, is present in saliva (1, 2, 3) and both gp-340 and salivary agglutinin are encoded by the gene DMBT1. 

Application 1

ELISA
HYB 213-06 can be used in ELISA (2).

Application 2

WB
In Western blotting after SDS-PAGE HYB 213-06 reacts strongly with gp-340 in non-reduced forms only. A dilution guideline of 1/2000 has proved successful (1, 2, 3,4).

Application 3

IHC
HYB 213-06 can be used in IHC (1, 2).