- $410
- BioPorto
- 丹麦
- MON T-11
- 2025年07月08日
- ELISA, WB, IHC-F, IP
- Human
- 见官方网站
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
见官方网站
- 亚型：
见官方网站
- 形态：
冻干粉或液体
- 保存条件：
-20ºC
- 克隆性：
多克隆
- 标记物：
见官方网站
- 适应物种：
见官方网站
- 保质期：
1年
- 抗原来源：
见官方网站
- 目录编号：
MON T-11
- 级别：
见官方网站
- 库存：
30
- 供应商：
上海泽叶生物科技有限公司
- 宿主：
Human
- 应用范围：
ELISA, WB, IHC-F, IP
- 浓度：
1 mg/ml
- 靶点：
见官方网站
- 抗体英文名：
Anti-Tissue plasminogen activator (human, tPA)
- 抗体名：
Anti-Tissue plasminogen activator (human, tPA)
- 规格：
200ug
Anti-Tissue plasminogen activator (human, tPA)
Bioporto是一家体外诊断公司，专业为临床和科研提供一系列诊断试剂盒和抗体。其领先的产品组合包括了用于急性肾功能损伤诊断用的NGAL以及其它疾病检测用抗体。官方网站：www.bioporto.com
- Cat. No.
- MON T-11
- Product name
- Anti-Tissue plasminogen activator (human, tPA)
- Description
-
Mouse monoclonal antibody
- Specificity
-
MON T-1 is specific for human tPA. No reaction is seen with human urokinase plasminogen activator (uPA) when tested by ELISA, immunoblotting and enzyme inhibition and no reaction with any other human plasma proteins is seen when tested by immunoblotting. MON T-1 reacts with single- and two-chain tPA
- Immunogen
-
Native human tPA
- Application
- ELISA, WB, IHC-F, IP
- Species reactivity (positive)
- Human
- Species reactivity (negative)
- Not determined
- Subclass
-
IgG1
- Gene ID
- 5327
- Clone number
- T-1
- Epitope
-
MON T-1 binds to the A-chain of tPA
- Content
-
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.14 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
-
Tissue plasminogen activator (tPA) is a serine protease which converts the abundant proenzyme plasminogen to active plasmin. It plays a key role in thrombolysis and several neurobiological processes.
- Other information
- This product is not for further manufacture.
- Application 1
-
ELISA
MON T-1 can be used in ELISA (1). - Application 2
-
WB
MON T-1 reacts with non-reduced tPA but not with reduced tPA in Western blotting. It inhibits the enzymatic activity of tPA. - Application 3
-
IHC
For immunohistochemistry applications MON T-1 can be used on frozen sections. (2, 3) - Application 4
-
IP
MON T-1 is suitable immunopercipitation
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文献和实验Use of Tissue-Plasminogen Activator as a Reporter Gene
Throughout the past six or seven years, our ability to study and understand the process of eukaryotic gene expression has been greatly enhanced by the use of reporter genes. In essence, a reporter gene encodes a protein product
RFLP Molecular Analysis of the Urokinase-Type Plasminogen Activator Gene
attachments. One such enzyme, the serine protease urokinase-type plasminogen activator (uPA), converts enzymatically inactive plasminogen into the widely acting protease plasmin, which degrades several extracellular matrix components and also activates
as the Northern blot (2 ). Both are, then, often key elements in establishing the identity of nucleic acids of interest. Northern blot analysis was used by us as a tool in order to answer the question whether or not the nuclear transcripitional apparatus of human
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