北京现货重组人BCL2L2(Bc1-w)促销

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名称：北京现货重组人BCL2L2(Bc1-w)促销
英文名：Recombinant Human B Cell Lymphoma/Leukemia w
规格：10μg|50μg|500μg|1mg
产地：国产|进口
品牌：百奥莱博
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Ala2-Thr172在C端含有His标签。

BCL2L2/Bc1-w质量控制：＞95%(还原性SDS-PAGE)

BCL2L2/Bc1-w制剂：液体

BCL2L2/Bc1-w保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于BCL2L2/Bc1-w：
Bcl-2-like protein 2 (BCL2L2) belongs to the Bcl-2 family. BCL2L2 is highly expressed in thebrain, spinal cord, testis, pancreas, heart, spleen, and mammary glands. BCL2L2 is a peripheral membrane protein containing three motifs, BH1, BH2 and BH4. The BH4 motif appears to be involved in the anti-apoptotic function. The BH1 and BH2 motifs form a hydrophobic groove which acts as a do*(代"c")king site for the BH3 domain of some pro-apoptotic proteins. BCL2L2 promotes cell survival and blocks dexamethasone-induced apoptosis. Furthermore, BCL2L2 mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.

关于北京现货重组人BCL2L2(Bc1-w)促销的更详细说明，请致电我公司咨询，我们将以最饱满的热情为您提供解答，此外，我公司专业供应下列产品：
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北京现货重组人BCL2L2(Bc1-w)促销关键词：重组人BCL2L2,重组BCL2L2,重组人Bc1-w,重组人BCL2L2蛋白,JN1911


·重组小鼠ULBP-1
编号：JN1375
英文名称：Recombinant Mouse UL16 Binding Protein-1/NKG2D ligand 1
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Pro26-Thr211在C端含有His标签。

ULBP-1质量控制：＞95%(还原性SDS-PAGE)

ULBP-1制剂：冻干品

ULBP-1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

ULBP-1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于ULBP-1：
Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocomp*(代"a")tibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. It can activate multiple signaling pathways in primary NK cells, gamma delta T cells, and CD8+ alpha beta T cells, resulting in the production of cytokines and chemokines.ULBP1 is expressed in wide range of tissues including heart, brain, lung, liver, bone marrow and some tumor cells, T-cells, B-cells, As an unconventional member of the MHC class I family, ULBP1 is able to interact with soluble CMV glycoprotein UL16 in CMV infected cells. The interaction with UL16 blocked the interaction with the NKG2D receptor, and thus might escape the immune surveillance. Furthermore, UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. The ULBP1 regulation may have implications for development of new therapeutic strategies against cancer cells.


北京现货重组人BCL2L2(Bc1-w)促销关键词：重组人BCL2L2,重组BCL2L2,重组人Bc1-w,重组人BCL2L2蛋白,JN1911

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