JN1456型重组小鼠Soggy-1(DkkL1)促销

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括JN1456型重组小鼠Soggy-1(DkkL1)促销在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：JN1456型重组小鼠Soggy-1(DkkL1)促销
规格：10μg|50μg|500μg|1mg
产地：国产|进口
品牌：百奥莱博
编号：JN1456
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu21-Leu230在C端含有His标签。

Soggy-1/DkkL1 质量控制：＞95%(还原性SDS-PAGE)

Soggy-1/DkkL1 制剂：冻干品

Soggy-1/DkkL1 保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Soggy-1/DkkL1 复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Soggy-1/DkkL1 ：
The glycoprotein Dickkopf-like1, also known as soggy-1, is a member of Dickkopf (Dkk) family which modulates Wnt signaling by binding to the Wnt co-receptor lipoprotein receptor-related protein (Lrp) via two Cys-rich regions. Dkkl1 shows unique homology to a discrete region in Dkk3, however, it lacks the Lrp binding region that enables Wnt modulation. Dkkl1 expression is gradually upregulated during the development of mouse testis and corresponds to the mouse spermatogenesis. Mouse Dkkl1 is detected in the embryo, as well as in the developing skeleton, eyes and neural tissue. In adult animals the expressionof Dkkl1 is specific for spermatocytes and spermatids, where it regulates spermatocyte apoptosis mediated by Fas death ligand (FasL). Dkkl1 plays a critical role in male mammalian spermatogenesis.

除JN1456型重组小鼠Soggy-1(DkkL1)促销外，我公司正在打折促销以下产品：

·重组小鼠CD47(IAP)(白细胞表面抗原CD47)
编号：JN1635
英文名称：Recombinant Mouse Leukocyte surface antigen CD47
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gln19-Pro158在C端含有His标签。

CD47/IAP质量控制：＞95%(还原性SDS-PAGE)

CD47/IAP制剂：冻干品

CD47/IAP保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CD47/IAP复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CD47/IAP：
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD) with a single Ig‑like domain, five membrane-spanning regions with short intervening loops, and C‑terminal cytoplasmic tail. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important role in memory formation and synaptic plasticity in the hippocampus. As a receptor for SIRPA, it binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cellcell adhesion, it enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. It may play a role in membrane transport and/or integrin dependent signal transduction. It also prevents premature elimination of red blood cells.


JN1456型重组小鼠Soggy-1(DkkL1)促销关键词：JN1456,重组小鼠Soggy-1蛋白,重组小鼠DkkL1,重组Soggy-1


·T4多聚核苷酸激酶(T4 PNK)
编号：JN0067
英文名称：T4 Polynueleotide Kinase
规格：200U×5
  该酶能够催化磷酸在γ-位和双链/单链DNA或RNA的5´-羟基末端以 及3´-单磷酸核苷间进行转移和交换：5´-OH + NTP 5´-P + NDP;
  该酶还具有3´磷酸酶活性，将3´-磷酸基团从寡核苷酸的3´磷酸 末端、脱氧3´-单磷酸核苷和脱氧3´-二磷酸核苷上水解掉。

产品组成：

 

组份	体积
T4 PNK（10U/μl）	20μl
10×T4 PNK Reaction Buffer	1ml
10mM ATP	50μl

产品用途：
1、引物或PCR产物的5´末端磷酸化以便进行连接反应。（参见实验方案）
2、合成DNA接头 (Linker) 的5´末端磷酸化以便进行连接反应。
3、DNA及RNA 5´末端的标记，用作寡核苷酸探针。

使用建议：
1、1×T4 PNK反应缓冲液中不含ATP，需在反应体系中加入终浓度为1mM的ATP，也可以使用T4 DNA连接酶的反应液代替。
2、铵离子强烈抑制T4 PNK活性，故DNA应溶于不含铵盐的溶液中。

活性定义：以Micr℃℃cal Nuclease处理的小牛胸腺DNA为底物，在37℃，pH7.6的条件下，30分钟内使1 nmol 的[γ-32P]ATP掺入酸不溶性沉淀物所需要的酶量定义为1个活性单位（U）。

质量保证：经多次柱纯化，SDS-PAGE胶检测仅可见清晰单一的目的条带；PCR方法检测无大肠杆菌DNA残留，无核酸内、外切酶污染。


JN1456型重组小鼠Soggy-1(DkkL1)促销关键词：JN1456,重组小鼠Soggy-1蛋白,重组小鼠DkkL1,重组Soggy-1


·重组人PITPNA(磷脂酰肌醇转运蛋白α)
编号：JN0856
英文名称：Recombinant Human Phosphatidylinositol Transfer Protein alpfa Isoform
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Asp270在N端含有His标签。

PITPNA质量控制：＞95%(还原性SDS-PAGE)

PITPNA制剂：液体

PITPNA保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于PITPNA：
Phosphatidylinositol Transfer Protein α Isoform (PITPNA) is found in the cytoplasm and belongs to the PtdIns transfer protein family. PITPNA is a ubiquitous and highly conserved protein in multicellular eukaryotes that catalyzes the exchange of phospholipids between membranes and participates in cellular phospholipid metabolism, signal transduction and vesicular trafficking in vivo. It is expressed in a wide range of tissues and implicated in phospholipase C signaling and in the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP3) by phosphoinositide-3-kinase.

北京百莱博科技有限公司是分子生物学试剂产品的专业生产供应销*(代"售")商，恭候您的咨询选购JN1456型重组小鼠Soggy-1(DkkL1)促销。