重组人CRTAM说明书

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、医疗及其他非科研用途。

北京百奥莱博供应的重组人CRTAM说明书用于科研目的生化试验项目，本产品质量好，且极具价格优势，深为用户称道，了解更多重组人CRTAM等分子生物学试剂产品请联系我司咨询订购。

名称：重组人CRTAM说明书
英文名：Recombinant Human Cytotoxic and Regulatory T-Cell Molecule
产地：国产|进口
编号：JN0518
品牌：百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser18-Ser286在C端含有His标签。

CRTAM质量控制：＞95%(还原性SDS-PAGE)

CRTAM制剂：冻干品

CRTAM保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CRTAM复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CRTAM：
Cytotoxic and Regulatory T-Cell Molecule (CRTAM) is a member of Nectin family under the immunoglobulin superfamily that is expressed by activated CD8+ and NK T cells. CRTAM is found in spleen, thymus, small intestine, peripheral blood, and it is highly expressed by Purkinje cells of the cerebellum. CRTAM is a type I transmembrane glycoprotein containing one Ig-like C2-type domain and one Ig-like V-type domain in its extracellular domain, while its cytoplasmic region shows a potential class I PDZ domain. CRTAM is expressed as a homodimer on the cell surface but does not show homotypic binding in trans. The high affinity of CRTAM/IGSF4 adhesion allows CRTAM to disrupt IGSF4 homotypic interactions. IGSF4 and T cell receptor coengagement of CD8+ cells expressiong CRTAM induces increased IFNγ or IL-22 production.

更多有关重组人CRTAM说明书的价格及使用说明等，请联系我们的业务经理王欣女士咨询，我公司还销*(代"售")以下产品：

·重组人OX40(TNFRSF4)(CD134)(C端His标签)
编号：JN0490
英文名称：Recombinant Human OX40L receptor
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu29-Ala216在C端含有His标签。

OX40/TNFRSF4/CD134质量控制：＞95%(还原性SDS-PAGE)

OX40/TNFRSF4/CD134制剂：冻干品

OX40/TNFRSF4/CD134保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

OX40/TNFRSF4/CD134复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于OX40/TNFRSF4/CD134：
OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.


重组人CRTAM说明书关键词：百奥莱博,重组CRTAM,重组人CRTAM蛋白,Recombinant Human Cytotoxic and Regulatory T-Cell ,JN0518


·重组人泛素结合酶E2-A(UBCE2A)
编号：JN1962
英文名称：Recombinant Human Ubiquitin-Conjugating Enzyme E2 A
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Cys152在N端含有GST标签和His标签

UBCE2A质量控制：＞95%(还原性SDS-PAGE)

UBCE2A制剂：液体

UBCE2A保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于UBCE2A：
Ubiquitin-Conjugating Enzyme E2 (UBCE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBCE2A catalyzes the covalent attachment of ubiquitin to other proteins. UBCE2A is required for postreplication repair of UV-damaged DNA. UBCE2A Interacts with RAD18 and WAC.


重组人CRTAM说明书关键词：百奥莱博,重组CRTAM,重组人CRTAM蛋白,Recombinant Human Cytotoxic and Regulatory T-Cell ,JN0518

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