重组人CRTAM

特别提示：包括重组人CRTAM在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人CRTAM
英文名称：Recombinant Human Cytotoxic and Regulatory T-Cell Molecule
产品货号：JN0518
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser18-Ser286在C端含有His标签。

CRTAM质量控制：＞95%(还原性SDS-PAGE)

CRTAM制剂：冻干品

CRTAM保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CRTAM复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CRTAM：
Cytotoxic and Regulatory T-Cell Molecule (CRTAM) is a member of Nectin family under the immunoglobulin superfamily that is expressed by activated CD8+ and NK T cells. CRTAM is found in spleen, thymus, small intestine, peripheral blood, and it is highly expressed by Purkinje cells of the cerebellum. CRTAM is a type I transmembrane glycoprotein containing one Ig-like C2-type domain and one Ig-like V-type domain in its extracellular domain, while its cytoplasmic region shows a potential class I PDZ domain. CRTAM is expressed as a homodimer on the cell surface but does not show homotypic binding in trans. The high affinity of CRTAM/IGSF4 adhesion allows CRTAM to disrupt IGSF4 homotypic interactions. IGSF4 and T cell receptor coengagement of CD8+ cells expressiong CRTAM induces increased IFNγ or IL-22 production.

除了重组人CRTAM,，我公司还供应以下相关产品：
 

货号	名称	规格
JN0272	重组人成纤维生长因子8e	10μg|50μg|500μg|1mg
JN1906	重组人酰基蛋白硫酯酶1(APT-1)	10μg|50μg|500μg|1mg
JN1910	重组人BCL2L1(Bcl-Xl)	10μg|50μg|500μg|1mg
JN1925	重组人β-防御素4A	10μg|50μg|500μg|1mg
JN1964	重组人泛素结合酶E2-H(UBCE2H)	10μg|50μg|500μg|1mg
JN1973	重组人Grancalcin蛋白	10μg|50μg|500μg|1mg
JN2030	重组人磷酸丙糖异构酶(TIM)	10μg|50μg|500μg|1mg
JN0548	重组人Vasorin	10μg|50μg|500μg|1mg
JN0592	重组人ST6GAL1	10μg|50μg|500μg|1mg
JN0608	重组人蛋白质二硫键异构酶A6(PDIA6)	10μg|50μg|500μg|1mg
JN0656	重组人睫状神经营养因子(CNTF)	10μg|50μg|500μg|1mg
JN0666	重组人卵黄膜外层蛋白1同系物(VMO1)(VMO-1)	10μg|50μg|500μg|1mg
JN0672	重组人NAD激酶(NADK)	10μg|50μg|500μg|1mg
JN0758	重组人GNRH2(促性腺激素释放素2)	10μg|50μg|500μg|1mg
JN0849	重组人平足蛋白(PDPN)(Podoplanin)(肾小球上皮细胞整合膜蛋白)	10μg|50μg|500μg|1mg
JN0867	重组人NFYA(核转录因子Y-α)	10μg|50μg|500μg|1mg
JN1053	重组人酪蛋白激酶γ2(CSNK1G2)	10μg|50μg|500μg|1mg
JN1234	重组人C2orf7(PRADC1)	10μg|50μg|500μg|1mg
JN1260	重组人EGFR(HER1)(表皮生长因子受体)(C端带His标签)	10μg|50μg|500μg|1mg
JN1442	重组小鼠IL-23R	10μg|50μg|500μg|1mg
JN1566	重组人IL-1R2(IL-1 RII)(C端带Fc标签)	10μg|50μg|500μg|1mg
JN1593	重组人信号调节蛋白α (SIRPα)	10μg|50μg|500μg|1mg
JN1790	重组人Serpin B1(丝氨酸蛋白酶抑制剂B1)	10μg|50μg|500μg|1mg
JN1821	重组人CD55(DAF)	10μg|50μg|500μg|1mg
JN1891	重组小鼠CD112(nectin2)	10μg|50μg|500μg|1mg
MQ0100	重组人RanTes(CCL5)	100μg
MQ0116	重组人骨形态发生蛋白4(BMP4)	100μg