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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
ICodonolactone; 8β-Hydroxyasterolide
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
73030-71-4
- 规格:
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥528.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥480.0 |
| 规格: | 10 mg | 产品价格: | ¥730.0 |
| 规格: | 25 mg | 产品价格: | ¥1200.0 |
| 规格: | 50 mg | 产品价格: | ¥1700.0 |
| 规格: | 100 mg | 产品价格: | ¥2500.0 |
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Atractylenolide III
CAS No. : 73030-71-4
MCE 国际站:Atractylenolide III
产品活性:Atractylenolide III (ICodonolactone) 是白术根茎主要成分,有诱导肺癌细胞凋亡 (apoptosis) 活性。Atractylenolide III 是一种具有口服活性的胃保护剂。
研究领域:Apoptosis
作用靶点:Apoptosis
In Vitro: Atractylenolide III (1-100 μM, 48 h ) induces cell apoptosis, and induces the activation of caspase-3 and caspase-9 and cleavage of PARP in A549 cells.
Atractylenolide III (1-100 μM, 72 h) inhibits proliferation and angiogenesis (tube formation) in HUVECs.
Atractylenolide III (1-100 μM) inhibits thymic stromal lymphopoietin (TSLP)-induced production of proinflammatory cytokines (IL-6, IL-1b, TNF-α, and IL-8) in HMC-1 cells.
In Vivo: Atractylenolide III (5 and 10 mg/kg, p.o.) shows gastroprotective effects and reduces 70% ethanol-induced gastric ulcer in rats.
Atractylenolide III (30 mg/kg, oral gavage for 14 days or 28 days) reduces depressive- and anxiogenic-like behaviors in rat depression models in Lipopolysaccharide (LPS) (HY-D1056) and chronic unpredictable mild stress (CUMS) induced rat depression model.
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文献和实验type-iii. domain 913 1009 fibronectin type-iii. mod_res ?24 ?24 blocked. carbohyd 71 71 potential. carbohyd 199 199 potential. carbohyd 456 456 potential. carbohyd 472 472 potential. carbohyd 493 493 potential. carbohyd 520 520 potential
性不是首先考虑的,这与自噬的应急特性是相适应的。 6)自噬的保守性:由于自噬有利于细胞的存活,因此无论是物种间、还是各细胞类型之间(包括肿瘤细胞),自噬都普遍被保留下来(谁不喜欢留一手呢?)。 参考综述: Autophagy fights disease through cellular self-digestion.pdf http://www.namipan.com/d/4c78fe31cb24080cd7630639c121cd71b24c9b56fbdf
Identification of Proteins in Complex Mixtures Using Liquid Chromatography and Mass Spectrometry
. Dongr, A.R., Eng, J.K., and Yates, J.R. III. 1997. Emerging tandem‐mass‐spectrometry techniques for the rapid identification of proteins. Trends Biotechnol. 15:418‐425.
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