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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
Isochlorogenic acid C
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
57378-72-0
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg/500 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥432.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥170.0 |
| 规格： | 5 mg | 产品价格： | ￥380.0 |
| 规格： | 10 mg | 产品价格： | ￥600.0 |
| 规格： | 25 mg | 产品价格： | ￥1028.0 |
| 规格： | 50 mg | 产品价格： | ￥1488.0 |
| 规格： | 100 mg | 产品价格： | ￥2225.0 |
| 规格： | 500 mg | 产品价格： | ￥5488.0 |
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4,5-Dicaffeoylquinic acid
CAS No. : 57378-72-0
MCE 国际站：4,5-Dicaffeoylquinic acid
产品活性：4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) 是一种抗氧化剂，可从 Gynura divaricata 和 Laggera alata 中分离获得。4,5-Dicaffeoylquinic acid 能减少 2 型糖尿病小鼠胰岛细胞凋亡 (apoptosis)，改善胰腺功能，对酵母 α-葡萄糖苷酶 (α-glucosidase) 有明显的抑制活性。4,5-Dicaffeoylquinic acid 通过阻滞细胞周期来抑制前列腺癌细胞增殖。4,5-Dicaffeoylquinic acid 还具有抗凋亡、抗损伤和抗乙型肝炎病毒 (HBV)的作用。
研究领域：Anti-infection | Metabolic Enzyme/Protease | Apoptosis
作用靶点：HBV | Endogenous Metabolite | Apoptosis | Glucosidase
来源：植物 | 豆科 | 维吉豆状鲍迪豆 | 植物 | 菊科
In Vitro: 4,5-Dicaffeoylquinic acid (0.1~100 µM; 72 h) has dose-dependent inhibitory activity against DU-145 prostate cancer cells, and induces cell cycle arrest, also induces inactivation of Bcl-2.
4,5-Dicaffeoylquinic acid (1~100 µg/mL; 48 h) has anti-apoptotic effect in D-GalN-challenged HL-7702 hepatocytes, and improves significantly cell viability at concentrations of 10 to 100 µg/mL.
4,5-Dicaffeoylquinic acid (1~100 µg/mL; 4 days) inhibits significantly expressions of HBsAg and HBeAg, and produces the maximum inhibition rates of 86.93 and 59.79% at 100 µg/mL on expressions of HBsAg and HBeAg, respectively.
In Vivo: 4,5-Dicaffeoylquinic acid enhances the expression of GLUT2, GK, and PDX-1 protein, and effectively alleviate glycaemia and insulin resistance and enhance insulin sensitivity in type 2 diabetic mice.
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文献和实验Two dimensional peptide mapping
will probably go down. After exposure, cut out the membrane piece of interest and soak it immediately in 0.5% PVP-360 (Polyvinylpyrrolidone, MW360) in 100mM acetic acid for 30 min. at 37°C. If you don't do this, your yield will be poor. This may result
. This part of the reaction is carried out at or near the optimal temperature required by the thermostable DNA polymerase. When using Taq DNA polymerase this temperature is 72-78°C and lasts about 1 minute for every 1000 bp of product. Depending upon the annealing
5030) CO2 cell culture incubator 50 ml Nunc/Falcon tubes 15 ml Nunc/Falcon tubes KCl (0.075 M, 0.055% ?) Fixative (methanol/acetic acid 3 : 1) glass microscopy slides Amounts per 5 ml blood: 40 ml RPMI 1640 Medium 10 ml FCS (20%)
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