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- 2025年07月16日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 yearsIn solvent: -80°C, 6 months; -20°C, 1 month
- 英文名：
19-Norethindrone acetate
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
51-98-9
- 规格：
10 mM * 1 mL/100 mg/500 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥550.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥500.0 |
| 规格： | 500 mg | 产品价格： | ￥900.0 |
Norethindrone acetate
产品活性：Norethindrone acetate is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.
研究领域：Others
作用靶点：Progesterone Receptor
In Vivo: Norethindrone acetate could be a cost-effective alternative with relatively mild side effects in the treatment of symptomatic endometriosis. Subjects treated with norethindrone acetate obtain dysmenorrhea and noncyclic pelvic pain relief[1]. Norethindrone acetate alone is a well-tolerated, effective option to manage pain and bleeding for all stages of endometriosis. Post-Norethindrone acetate bleeding scores are improved regardless of prior hormonal regimen, and post-Norethindrone acetate pain scores improved in all patients except for those previously prescribed GnRH-agonist plus add-back[2]. Norethindrone acetate shows low acute toxicity in experimental animals and is consistent with the lack of toxicity seen in humans. Administration of norethindrone acetate alone to rodents at several multiples of the human dose results in no treatment related mortality, hematological changes, behavioral changes, or organ pathology[3]. Norethindrone acetate administration leads to significant and proportional reductions of the concentrations of triglycerides, cholesterol and phospholipids of plasma lipoproteins of density <1.006 of rats fed a high carbohydrate diet. Norethindrone acetate (0.1 mM) also significantly inhibits the incorporation of both palmitate and glycerol into triglycerides of isolated hepatocytes from fed rats[4].
相关产品：FDA-Approved Drug Library Mini | FDA-Approved Drug Library | Bioactive Compound Library Plus | Mifepristone | Progesterone | Medroxyprogesterone (acetate) | Ulipristal acetate | Dydrogesterone | Drospirenone | Tanaproget | Megestrol Acetate | Dienogest | Altrenogest | Chlormadinone acetate | Desogestrel | Ethynodiol diacetate | Gestodene | Nestoron | Gestonorone Capronate
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