N-AcetylprocainamideN-乙酰普鲁卡因胺,

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N-Acetylprocainamide

CAS No. : 32795-44-1

MCE 国际站：N-Acetylprocainamide

产品活性：N-Acetylprocainamide 是第三代抗心律失常剂，能够抑制 K⁺ 通道。

研究领域：Membrane Transporter/Ion Channel  |  Metabolic Enzyme/Protease

作用靶点：Potassium Channel  |  Drug Metabolite

In Vitro: N-Acetylprocainamide is a K⁺ blocker. N-Acetylprocainamide decreases the tensions induced by K⁺ and methacholine. The pIC₅₀ values for N-acetylprocainamide against the contractions induced by 0.3 and 1 μM methacholine are 2.80 ± 0.03 and 2.65 ± 0.02, respectively. And such a relaxant effect of N-Acetylprocainamide is inhibited by K⁺ channel blockers. N-Acetylprocainamide shows no effect on Na⁺ absorption or Cl^- secretion.

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