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- 库存:
99
- 供应商:
Cloud-Clone
- 英文名:
Active Calpain 1, Large Subunit (CAPN1)
- 规格:
50ug
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文献和实验Purification and Characterization of Crustacean Calpain-like Proteinases
Calcium-dependent cysteine proteinases (CDPs or calpain-like proteinases) constitute a large family of related proteins in the tissues of invertebrate species. They vary in native mass from 59 kDa for lobster muscle CDP III to 520 kDa
Cleavage by granzyme B, caspase-6, caspase-8 and caspase-10 generates the two active subunits. Additional processing of the propeptides is likely due to the autocatalytic activity of the activated protease. Active heterodimers between the small subunit
a central role in eukaryotic cells since it is responsible for the degradation of specific proteins involved in a large range of cellular processes. Analysis of proteasome mechanisms of action, or in vitro reconstitution, or dissection of the complex
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