- ￥3000 - 3999
- Abbiotec
- 美国
- 250301
- 2025年07月14日
- E, WB
- Mouse
- H
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
C5 isolated from human plasma
- 亚型：
Mouse IgG1/k
- 形态：
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
- 保存条件：
Store at 4°C.
- 克隆性：
单克隆抗体
- 标记物：
见下方详细说明
- 适应物种：
H
- 宿主：
Mouse
- 应用范围：
E, WB
- 浓度：
见详细说明信息
- 靶点：
C5 Complement (12F3)
- 抗体英文名：
C5 Complement (12F3) Antibody
- 抗体名：
C5 Complement (12F3)抗体
- 规格：
0.2 mg
C5 Complement (12F3) Antibody产品详细介绍：
| 产品名称： | C5 Complement (12F3) Antibody |
| 说明书： | http://www.abbiotec.com/antibodies/c5-complement-12f3-antibody【参考图片】 |
| 货号： | 250301 |
| 规格： | 0.2 mg |
| 产品描述： | C5 is part of the membrane attack complex (MAC) of the complement system. C5 is split into C5a and C5b by the C5 convertases from the classical and the alternative complement pathway and the C5b fragment initiates the assembly of the terminal MAC (C5b-C9). The molecular mass of C5 is 190 kDa. This antibody is specific for human C5. No reaction is seen with plasma from patients deficient in C5. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | Mouse IgG1/k |
| 免疫原： | C5 isolated from human plasma |
| 适用物种： | H |
| 应用范围： | E, WB |
| 应用说明： | Product Cat. No. 250301 reacts strongly with C5 from normal human plasma and does not with plasma from patients deficient in C5, when tested in sandwich ELISA in combination with a polyclonal antibody against C5. Product Cat. No. 250301 reacts in Western blot with C5 in normal human plasma in nonreduced form only (PEG precipitated C5), but no reaction is seen with plasma from C5-deficient patients. E: 1:6,000; WB: 1:500 |
| 别名： | Complement component C5; Complement component 5 preprotein |
| 形态： | Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件： | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 参考文献： |
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文献和实验Purification of Human Complement Protein C5
Complement C5 is cleaved by proteolysis in the terminal phase of complement activation generating the pro-inflammatory C5a and membrane attack complex nucleator C5b. Whereas purification of its paralogues C3 and C4 from plasma is relatively
Quantification of Complement C5b-9 Binding to Cells by Flow Cytometry
Interaction of the complement system, directly or indirectly (e.g., via antibodies), with cells activates the early and late complement components and culminates in the deposition of a membrane-spanning C5b-9 complex on the cell surface
补体成分 C5(C5a/C5b) 补体成分：C5 血清浓度(μg/ml)：70 分子量(kDa)：190 亚单位(链)及分子量(kDa)：α∶115；β∶75 激活产物：C5a；C5b 生物学活性：C5a 强的过敏毒素作用、趋化作用、促代谢作用及免疫调节作用 C5b
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