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FGFR1 Antibody

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  • ¥3000 - 3999
  • Abbiotec已认证
  • 美国
  • 2025年07月15日
  • E, WB, IHC, FC
  • Rabbit
  • H, M, R
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human FGFR1.

    • 亚型

      Rabbit Ig

    • 形态

      Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

    • 保存条件

      Store at -20°C.

    • 克隆性

      多克隆抗体

    • 标记物

      见下方详细说明

    • 适应物种

      H, M, R

    • 宿主

      Rabbit

    • 应用范围

      E, WB, IHC, FC

    • 浓度

      见详细说明信息

    • 靶点

      FGFR1

    • 抗体英文名

      FGFR1 Antibody

    • 抗体名

      FGFR1 Antibody

    • 规格

      0.1 mg

    产品细节图片1
    FGFR1 Antibody产品详细介绍:
    产品名称: FGFR1 Antibody
    说明书: http://www.abbiotec.com/antibodies/fgfr1-antibody【参考图片】
    货号: 250651
    规格: 0.1 mg
    产品描述: FGFR1 (Basic fibroblast growth factor receptor 1) is a membrane receptor for basic fibroblast growth factor (FGF2) and for acidic fibroblast growth factor (FGF1). Binding of FGF and heparin leads to receptor dimerization and autophosphorylation at 7 tyrosine residues in the cytoplasmic tail. Phosphorylation of tyrosine 653 and 654 are important for catalytic activity while other sites may provide docking sites for downstream signaling components such as Crk and PLCgamma. FGFR1 also interacts with SHB, KLB, FGF23, GRB10. FGFR1 activation influences mitogenesis and differentiation of various cell types. Mutations and chromosomal aberrations are associated with various disorders including Pfeiffer Syndrome, idiopathic hypogonadotropic hypogonadism, Kallmann syndrome type 2, osteoglophonic dysplasia, non-syndromic trigonocephaly, stem cell leukemia lymphoma syndrome and stem cell myeloproliferative disorder.
    克隆类型: Rabbit Polyclonal Antibody
    亚型: Rabbit Ig
    免疫原: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human FGFR1.
    适用物种: H, M, R
    应用范围: E, WB, IHC, FC
    应用说明: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; FC: 1:50-1:200
    别名: FGFR1; Fibroblast growth factor receptor 1; Basic fibroblast growth factor receptor 1; FGFR-1; bFGF-R-1; Proto-oncogene c-Fgr; Fms-like tyrosine kinase 2; c-fgr; CD331; FLT-2; FGFBR; FLG; FLT2
    形态: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
    保存条件: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
    参考文献:

    ABBIOTEC产品提供质量保证,提供完善的售后和技术支持,ABBIOTEC产品正品包装:
    产品细节图片2 产品细节图片3

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    图标文献和实验
    相关实验
    • Generation of Antibody Molecules Through Antibody Engineering

      been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional

    • The Antibody Molecule

      The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera

    • Antibody Storage

        General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease

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