Human ICAM-1,Recombinant Prote

产品描述：
Intracellular adhesion molecules (ICAM proteins) are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM-1 engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation. ICAM-1 acts as a cellular receptor for rhinovirus and also interacts with human herpes virus 8 MIR2 protein. Homozygotes with ICAM1-Kalifi Met-56 seem to have an increased risk for cerebral malaria. Recombinant ICAM-1 comprises a 455 amino acid fragment (28-483) corresponding to the mature extracellular domain of the ICAM-1 protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
形 态 ：
Each vial contains 0.01 mg protein (liquid) in PBS pH7.4, 50% glycerol. Final concentration 0.1-1 mg/ml.
来 源 ：
E. coli
别 名 ：
ICAM-1; Intercellular adhesion molecule ; ICAM-1; Major group rhinovirus receptor; CD54
纯 度 ：
Purity > 95% as determined by reducing and non-reducing SDS-PAGE, Bradford assay, Western blot and ELISA.
分子量 ：
59.97 kDa
应 用 ：E, WB

保存条件 ：
Store at -20°C. Product is guaranteed one year from the date of shipment.

产品链接 ：http://www.abbiotec.com/proteins/human-icam-1