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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Protein S isolated from human plasma
- 亚型:
Mouse IgG2b/k
- 形态:
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
- 保存条件:
Store at 4°C.
- 克隆性:
单克隆抗体
- 标记物:
见下方详细说明
- 适应物种:
H
- 宿主:
Mouse
- 应用范围:
E
- 浓度:
见详细说明信息
- 靶点:
Protein S (8D5)
- 抗体英文名:
Protein S (8D5) Antibody
- 抗体名:
Protein S (8D5)抗体
- 规格:
0.2 mg
Protein S (8D5) Antibody产品详细介绍:
| 产品名称: | Protein S (8D5) Antibody |
| 说明书: | http://www.abbiotec.com/antibodies/protein-s-8d5-antibody【参考图片】 |
| 货号: | 250397 |
| 规格: | 0.2 mg |
| 产品描述: | Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 µg/ml, with a half-life of approximately two days. About 40% of protein S in plasma is in a free form, wheraes 60% is complexed with C4b-binding Protein (C4BP). Only the free protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa. This antibody is specific for human protein S. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG2b/k |
| 免疫原: | Protein S isolated from human plasma |
| 适用物种: | H |
| 应用范围: | E |
| 应用说明: | Product Cat. No. 250397 reacts strongly in sandwich ELISA with protein S and a biotin-labeled antibody. Antibody binding is calcium-dependent and is optimal at 1 mM CaCl2 in Tris buffer. SDS-treatment abolishes the reactivity in dot blot. E: 1:20,000 |
| 别名: | Vitamin K-dependent protein S; PROS1; PROS |
| 形态: | Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件: | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: |
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文献和实验Protein S (PS) is a vitamin K-dependent plasma glycoprotein. Around 60–70% of PS in plasma is noncovalently bound to C4-binding protein (C4BP). Free PS functions as a cofactor that enhances the activity of activated protein C (APC
Analysis of the Protein S Gene in Protein S Deficiency
Protein S (PS) is a 71-kDa vitamin K-dependent glycoprotein first identified in human plasma by DiScipio and colleagues in 1977 (1 ), a year after the discovery of the anticoagulant protein C (PC) (2 ,3 ). A few years later, Walker
ANTIBODY BINDING TO PROTEIN A AND PROTEIN G
. A physicochemical study f protein G, a molecule with unique immunoglobulin G-binding properties. J. Biol. Chem. 261:10240-10247. Harlow, E. and Lane, D. 1988. Antibodies. A laboratory manual. Cold Spring Harbor Laboratory. Kronvall, G., Seal, U. S
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