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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Gliadin-related peptide (alpha-gliadin aa58-73, KLQPFPQPELPYPQPQ) coupled to immunogenic carrier protein PPD (tuberculin).
- 亚型:
Mouse IgG2a
- 形态:
Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
- 保存条件:
Store at 4°C.
- 克隆性:
单克隆抗体
- 标记物:
见下方详细说明
- 适应物种:
Pl
- 宿主:
Mouse
- 应用范围:
E
- 浓度:
见详细说明信息
- 靶点:
Gliadin Peptide (14D5)
- 抗体英文名:
Gliadin Peptide (14D5) Antibody
- 抗体名:
Gliadin Peptide (14D5)抗体
- 规格:
0.2 mg
Gliadin Peptide (14D5) Antibody产品详细介绍:
| 产品名称: | Gliadin Peptide (14D5) Antibody |
| 说明书: | http://www.abbiotec.com/antibodies/gliadin-peptide-14d5-antibody【参考图片】 |
| 货号: | 250437 |
| 规格: | 0.2 mg |
| 产品描述: | Celiac disease is associated with a CD4+ T-cell response to epitopes of gliadin presented by HLA-DQ2 or -DQ8 class II MHC molecules. These epitopes are present in a 33-mer peptide of wheat alpha-gliadin, residues 56-88, which is resistant to digestion and forms a substrate for tissue transglutaminase (TG2), generating the glutamic acid residues essential for binding to HLA-DQ2. The immunogen corresponds to a deamidated form of a region that includes the T-cell epitopes, including the immunodominant PQPQLPY region and two PXPQP motifs associated with binding to IgA from patients with celiac disease. Complete homology exists between residues 63-73, 70-80 and 77-87 of wheat alpha gliadin. This antibody reacts strongly with the deamidated peptide but cross-reacts about 5% with the non-deamidated peptide KLQPFPQPQLPYPQPQ |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | Mouse IgG2a |
| 免疫原: | Gliadin-related peptide (alpha-gliadin aa58-73, KLQPFPQPELPYPQPQ) coupled to immunogenic carrier protein PPD (tuberculin). |
| 适用物种: | Pl |
| 应用范围: | E |
| 应用说明: | Product Cat. No. 250437 reacts in ELISA with both the deamidated gliadin-related peptide (KLQPFPQPELPYPQPQ) and non-deamidated gliadin-related peptide (KLQPFPQPQLPYPQPQ) coated directly in microplate. The signal for the deamidated gliadin-related peptide is 20-fold higher. E: 1:64,000 |
| 别名: | Alpha gliadin; prolamin |
| 形态: | Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography. |
| 保存条件: | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 参考文献: |
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文献和实验Purification Of Anti Peptide Antibody
antibody that could contribute to staining background. The proportion in each pool varies with the peptide immunogen. The quality of the anti-peptide serum seems to increase with multiple boosts - the first bleed may be feeble.
Peptide Microarrays for Serum Antibody Diagnostics
antibody. A proposal for the diagnostic evaluation of fluorescence data obtained with the peptide microarray is also made.
Antibody Epitope Mapping Using SPOT Peptide Arrays
Information at the amino acid level about the epitopes of proteins recognized by antibodies or antibody fragments is important for their use as biological and diagnostic tools, therapeutic molecules, and for understanding molecular recognition
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