- ￥3000 - 3999
- Abbiotec
- 美国
- 251057
- 2025年11月25日
- FC
- Mouse
- H
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
mouse IgG2b
- 形态：
Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at 4°C.
- 克隆性：
单克隆
- 标记物：
见下方详细说明
- 适应物种：
H
- 保质期：
1-2年
- 目录编号：
251057
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Mouse
- 应用范围：
FC
- 浓度：
见详细说明信息
- 靶点：
CD11b (HI11b)
- 抗体英文名：
CD11b (HI11b) Antibody
- 抗体名：
CD11b (HI11b) Antibody
- 规格：
2 ml
CD11b (HI11b) Antibody产品详细介绍：
| 产品名称： | CD11b (HI11b) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 251057 |
| 规格： | 2 ml |
| 产品描述： | The CD11b (HI11b) antibody recognizes the 165-kDa integrin αM-chain associated with CD18, the 95-kDa integrinβ2, which form a heterodimer glycoprotein called CD11b/CD18 (Mac-1). Leukocytes express four CD11/CD18 integrins which include a common β2 subunit and distinctive α chains. Besides CD11b/CD18, the other three integrins are known as CD11a/CD18, CD11c/CD18 and CD11d/CD18. Expression of the CD11b subunit on the leukocyte cell surface requires the presence of the CD18 subunit. Patients who have mutated CD18 genes do not express cell membrane Mac-1 (or the other β2 integrins), a condition known as leukocyte adhesion deficiency 1 (LAD-1), in which patients have major problems with bacterial infections. Mac-1 is highly expressed on neutrophils and monocytes/macrophages, a subset of NK cells, and activated lymphocytes. Mac-1 operates as a phagocytic receptor, has a role in myeloid cell transmigration and is also a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and fibrinogen. |
| 克隆类型： | Mouse Monoclonal Antibody, PE-conjugated Antibody |
| 亚型： | mouse IgG2b |
| 免疫原： | |
| 适用物种： | H |
| 应用范围： | FC |
| 应用说明： | FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000 |
| 别名： | Integrin alpha-M; Leukocyte adhesion receptor MO1; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; Neutrophil adherence receptor; CD11 antigen-like family member B; CD11b antigen; ITGAM; CD11B; CR3A |
| 形态： | Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
| 参考文献： |
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文献和实验上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人可溶性CD11b ( sCD11b )ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 sCD11b 单抗包被于酶标板上，标准品和样品中的 sCD11b与单抗结合，加入生物
网络 四、Ⅲ型补体受体（CD11b/CD18） Ⅲ型补体受体（CR3）为由α、β两条肽链以非共价键结合而构成的异二聚体糖蛋白，分子量分别为165kDa和95kDa。CR3属于粘附分子整合素（integrin）家族中的成员，与淋巴细胞功能相关抗原-1（LFA-1）和CR4的结构极为相似，三者的β链完全相同（命名为CD18），而α链
Analyzing the Angiogenic Potential of Gr-1+CD11b+ Immature Myeloid Cells from Murine Wounds
healing, the most prominent subtypes are Gr-1+ CD11b+ cells that consist of progenitor cells and more differentiated granulocytes. Under certain conditions, these cells have the potential to strongly promote angiogenesis, and thus tissue repair
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