CD11b (HI11b) Antibody_CD11b (HI11b)抗体

CD11b (HI11b) Antibody_CD11b (

HI11b)抗体
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  • ¥3000 - 3999
  • Abbiotec已认证
  • 美国
  • 2025年11月25日
  • FC
  • Mouse
  • H
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    • 详细信息
    • 技术资料
    • 亚型

      mouse IgG2b

    • 形态

      Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

    • 保存条件

      Store at 4°C.

    • 克隆性

      单克隆

    • 标记物

      见下方详细说明

    • 适应物种

      H

    • 保质期

      1-2年

    • 目录编号

      251057

    • 级别

      超纯

    • 库存

      大量

    • 供应商

      Abbiotec

    • 宿主

      Mouse

    • 应用范围

      FC

    • 浓度

      见详细说明信息

    • 靶点

      CD11b (HI11b)

    • 抗体英文名

      CD11b (HI11b) Antibody

    • 抗体名

      CD11b (HI11b) Antibody

    • 规格

      2 ml

    CD11b (HI11b) Antibody_CD11b (
    CD11b (HI11b) Antibody产品详细介绍:
    产品名称: CD11b (HI11b) Antibody
    说明书: 点击查看详细说明及参考图片
    货号: 251057
    规格: 2 ml
    产品描述: The CD11b (HI11b) antibody recognizes the 165-kDa integrin αM-chain associated with CD18, the 95-kDa integrinβ2, which form a heterodimer glycoprotein called CD11b/CD18 (Mac-1). Leukocytes express four CD11/CD18 integrins which include a common β2 subunit and distinctive α chains. Besides CD11b/CD18, the other three integrins are known as CD11a/CD18, CD11c/CD18 and CD11d/CD18. Expression of the CD11b subunit on the leukocyte cell surface requires the presence of the CD18 subunit. Patients who have mutated CD18 genes do not express cell membrane Mac-1 (or the other β2 integrins), a condition known as leukocyte adhesion deficiency 1 (LAD-1), in which patients have major problems with bacterial infections. Mac-1 is highly expressed on neutrophils and monocytes/macrophages, a subset of NK cells, and activated lymphocytes. Mac-1 operates as a phagocytic receptor, has a role in myeloid cell transmigration and is also a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and fibrinogen.
    克隆类型: Mouse Monoclonal Antibody, PE-conjugated Antibody
    亚型: mouse IgG2b
    免疫原:
    适用物种: H
    应用范围: FC
    应用说明: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
    别名: Integrin alpha-M; Leukocyte adhesion receptor MO1; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; Neutrophil adherence receptor; CD11 antigen-like family member B; CD11b antigen; ITGAM; CD11B; CR3A
    形态: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
    保存条件: Store at 4°C. Product is guaranteed 6 months from the date of shipment.
    参考文献:

    ABBIOTEC产品提供质量保证,提供完善的售后和技术支持,ABBIOTEC产品正品包装:
    CD11b (HI11b) Antibody_CD11b ( CD11b (HI11b) Antibody_CD11b (

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