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重组人分泌型磷蛋白1(SPP1)销售

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  • ¥190 - 2190
  • 百奥莱博
  • 北京
  • JN0615-QNW
  • 2025年07月07日
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    • 详细信息
    • 技术资料
    • 保存条件

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    • 保质期

      长期

    • 英文名

      Recombinant Human Secreted Phosphoprotein 1

    • 库存

      622

    • 供应商

      北京百奥莱博科技有限公司

    特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、医疗及其他非科研用途。

    北京百奥莱博专注于生命科学和生物技术领域,致力于为客户提供包括重组人分泌型磷蛋白1(SPP1)销*(代"售")在内的一系列分子生物学试剂产品,并提供一系列相关的技术服务。


    名称:重组人分泌型磷蛋白1(SPP1)销*(代"售")
    规格:10μg|50μg|500μg|1mg
    品牌:百奥莱博
    英文名:Recombinant Human Secreted Phosphoprotein 1
    产地:国产|进口
    本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ile17-Asn314在C端含有His标签。

    SPP1质量控制:>95%(还原性SDS-PAGE)

    SPP1制剂:冻干品

    SPP1保存
    冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

    SPP1复溶
    打开试剂管前请先离心。
    复溶浓度推荐大于100 μg/ml。
    冻干蛋白请溶于ddH2O。
    复溶后,请根据用量分装冻存,避免反复冻融。

    关于SPP1
    Secreted Phosphoprotein 1 (SPP1) is a secreted multifunctional glycoprotein. Its putative functions include roles in bone metabolism, immune regulation, wound healing, cell survival, and tumor progression. Based on gene structure and chromosomal location, SPP1 is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family that also includes bone sialoprotein (BSP), dentin matrix protein 1 (DMP1), dentin sialophosphoprotein (DSPP), enamelin (ENAM), and matrix extracellular phosphoglycoprotein (MEPE). SPP1 is expressed in bone, although it is also expressed in other tissues. SPP1 acts as a cytokine that is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10. It is essential in the pathway that leads to type I immunity. Osteopontin has been implicated as an important factor in bone remodeling. Specifically, research suggests it plays a role in anchoring osteoclasts to the mineral matrix of bones. The fact that SPP1 interacts with multiple cell surface receptors which are ubiquitously expressed makes it an active player in many physiological and pathological processes including wound healing, bone turnover, tumorigenesis, inflammation and ischemia. Therefore, manipulation of plasma Osteopontin levels may be useful in the treatment of autoimmune diseases, cancer metastasis, osteoporosis and some forms of stress.

    重组人分泌型磷蛋白1(SPP1)销*(代"售")正在火爆热销,除此之外,为您推荐下别热销产品:

    ·重组人IL-23 R
    编号:JN1547
    英文名称:Recombinant Human Interleukin-23 Receptor
    规格:10μg|50μg|500μg|1mg
    本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Gly24-Asp353在C端带有Fc标签。

    IL-23 R质量控制:>95%(还原性SDS-PAGE)


    IL-23 R制剂:冻干品

    IL-23 R保存
    冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

    IL-23 R复溶
    打开试剂管前请先离心。
    复溶浓度推荐大于100 μg/ml。
    冻干蛋白请溶于ddH2O。
    复溶后,请根据用量分装冻存,避免反复冻融。

    关于IL-23 R
    Interleukin 23 receptor (IL23R) is a type I cytokine receptor for IL23. IL23 receptor complex is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-23. IL23, after binding to IL23R, activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes. IL23R is expressed on T cells, NK cells, dendritic cells, and macrophages. In fact, polymorphisms of the IL23R gene were reported to be associated with susceptibility to inflammatory diseases and autoimmune diseases such as psoriasis, multiple sclerosis, Gravess ophtalmopathy and inflammatory bowel diseases. The IL23R is known to be critically involved in the carcinogenesis of different malignant tumor.


    重组人分泌型磷蛋白1(SPP1)销*(代"售")关键词:重组人分泌型磷蛋白1,JN0615,重组人SPP1,重组分泌型磷蛋白1,重组人分泌型磷蛋白1蛋白


    ·重组小鼠β神经生长因子(β-NGF)(Ser122-Gly241)
    编号:JN0273
    英文名称:Recombinant Mouse beta-Nerve Growth Factor
    规格:10μg|50μg|500μg|1mg
    本品由我们的大肠杆菌表达系统制备,目的基因编码的Ser122-Gly241表达纯化而来。

    beta-NGF质量控制:>95%(还原性SDS-PAGE)。

    beta-NGF制剂:冻干品

    beta-NGF保存
    冻干蛋白可在-20℃长期保存,室温也可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天。
    复溶后建议分装冻存在-20℃,可保存3个月,应避免反复冻融。

    beta-NGF复溶
    1、试剂开盖前请先离心。
    2、复溶浓度应大于100 μg/ml.
    3、冻干蛋白溶于ddH2O中
    4、复溶后根据使用量分装保存,避免反复冻融。

    关于beta-NGF
    NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGF and 95.8% with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection and repair. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and symp*(代"a")thetic nervous systems.


    重组人分泌型磷蛋白1(SPP1)销*(代"售")关键词:重组人分泌型磷蛋白1,JN0615,重组人SPP1,重组分泌型磷蛋白1,重组人分泌型磷蛋白1蛋白


    ·重组人补体因子H相关蛋白5(CFHR5)
    编号:JN1113
    英文名称:Recombinant Human Complement Factor H-Related 5
    规格:10μg|50μg|500μg|1mg
    本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Glu19-Glu569在C端含有His标签。

    CFHR5质量控制:>95%(还原性SDS-PAGE)

    CFHR5制剂:冻干品

    CFHR5保存
    冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

    CFHR5复溶
    打开试剂管前请先离心。
    复溶浓度推荐大于100 μg/ml。
    冻干蛋白请溶于ddH2O。
    复溶后,请根据用量分装冻存,避免反复冻融。

    关于CFHR5
    Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.



    我公司正在打折促销分子生物学试剂全系列产品,恭候您的咨询选购重组人分泌型磷蛋白1(SPP1)销*(代"售")

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