重组小鼠脊灰病毒受体(PVR)(CD155) 分子生物学试剂

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北京百奥莱博专业生产销*(代"售")重组小鼠脊灰病毒受体(PVR)(CD155) 分子生物学试剂，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。

名称：重组小鼠脊灰病毒受体(PVR)(CD155) 分子生物学试剂
编号：JN1620
产地：国产|进口
品牌：百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Asp29-Leu348在C端含有His标签。

PVR/CD155质量控制：＞95%(还原性SDS-PAGE)

PVR/CD155制剂：冻干品

PVR/CD155保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

PVR/CD155复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于PVR/CD155：
Mouse poliovirus receptor (PVR, CD155) is a type I transmembrane (TM) glycoprotein that is a member of the nectin-related family of adhesion proteins within the immunoglobulin superfamily. It binds other molecules including vitronectin, Nectin3, DNAM1, CD96, and TIGIT, but does not bind homotypically. CD155 includes a 28 aa signal sequence, a 318 aa extracellular domain (ECD) with one N-terminal V-type and two C2-type Ig-like domains, a 24 aa TM segment and a 38 aa cytoplasmic tail. Epithelial, endothelial, and many immune cells show low CD155 expression. It is up-regulated on endothelia by IFNγ, and is highly expressed on immature thymocytes, lymph node dendritic cells, and tumor cells of epithelial and neuronal origin. On migrating cells, it is concentrated at the leading edge, where it binds basement membrane vitronectin, recruits Nectin-3-expressing cells, and cooperates with PDGF and integrin αvβ3 to promote cell migration. Binding of monocyte DNAM-1 to endothelial cell CD155 promotes transendothelial migration. Enhanced CD155 expression in tumor cells contributes to loss of contact inhibition and increased migration, but also allows tumor cell recognition and killing by DNAM-1or CD96 expressing NK cells.

重组小鼠脊灰病毒受体(PVR)(CD155) 分子生物学试剂正在火爆热销，除此之外，为您推荐下别热销产品：

·重组小鼠组织蛋白酶H(CTSH)
编号：JN1415
英文名称：Recombinant Mouse Cathepsin H
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Glu22-Val333在C端含有His标签。

CTSH质量控制：＞95%(还原性SDS-PAGE)

CTSH制剂：冻干品

CTSH保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

CTSH复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于CTSH：
Cathepsin H (CTSH), which can act both as an aminopeptidase and as an endopeptidase, is a lysosomal cysteine protease of the papain family. CTSH is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. CTSH is associated with various pathological conditions like human fibrous meningioma, colorectal cancer, arthritis, human prostate tumor and lung cancer. CTSH is associated with cancer progression because of their ability to degrade extracellular matrices facilitating invasion, angiogenesis and metastasis as is evident from numerous clinical reports and experimental models. The expression of CTSH is significantly increased in disease states such as in prostate tumors, sera of asthmatic patients, and mucosa of colorectal cancer patients.


重组小鼠脊灰病毒受体(PVR)(CD155) 分子生物学试剂关键词：重组小鼠脊灰病毒受体,重组小鼠PVR,重组小鼠CD155,重组小鼠脊灰病毒受体蛋白,JN1620

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重组小鼠脊灰病毒受体(PVR)(CD155) 分子生物学试剂关键词：重组小鼠脊灰病毒受体,重组小鼠PVR,重组小鼠CD155,重组小鼠脊灰病毒受体蛋白,JN1620

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