Recombinant Human Serpin A3/AACT (C534)
产品说明(Description)
Recombinant Human Serine Protease Inhibitor-clade A3 is produced by our Mammalian expression system and the target gene encoding His24-Ala423(Lys267Arg) is expressed with a 6His tag at the C-terminus.
Accession #: P01011
Known as: Alpha-1-Antichymotrypsin; ACT; Cell Growth-Inhibiting Gene 24/25 Protein; Serpin A3; SERPINA3; AACT
制剂(Formulation)
Lyophilized from a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, pH 7.5.
质量控制(Quality Control)
Purity: Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
复溶(Reconstitution)
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存(Storage)
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
背景(Background)
Serpin A3 belongs to the Serpin superfamily of serine protease inhibitors. Serpin A3 has been shown to inhibit some serine proteases, such as neutrophil cathepsin G and mast cell chymase. Serpin A3 is synthesized initially in the liver and secreted in plasma. Serpin A3 has been found in the amyloid plaques from the hippocampus of Alzheimer disease brains. In addition to, Serpin A3 is associated with liver disease and Parkinson disease and chronic obstructive pulmonary disease.
电泳(SDS-PAGE)
FOR RESEARCH USE ONLY