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Recombinant Human Ly6/C4.4A/LY

PD3
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  • ¥640 - 1760
  • 近岸蛋白(Novoprotein)已认证
  • 中国
  • C487
  • 2026年01月15日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 英文名

      Recombinant Human Ly6/C4.4A/LYPD3

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥640.0
    规格:50ug产品价格:¥1760.0
    规格:500ug产品价格:询价
    规格:1mg产品价格:询价

    Recombinant Human Ly6/C4.4A/LYPD3  (C487)

     

    产品说明(Description)

    Recombinant Human Ly6/PLAUR Domain-Containing Protein 3 is produced by our Mammalian expression system and the target gene encoding Leu31-His286 is expressed with a 6His tag at the C-terminus. 

    Accession #: O95274

    Known as: Ly6/PLAUR Domain-Containing Protein 3; GPI-Anchored Metastasis-Associated Protein C4.4A Homolog; Matrigel-Induced Gene C4 Protein; MIG-C4; LYPD3; C4.4A

     

    制剂(Formulation)

    Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

     

    质量控制(Quality Control)

    Purity:            Greater than 95% as determined by reducing SDS-PAGE.    

    Endotoxin:    Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

     

    复溶(Reconstitution)

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in distilled water.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

     

    保存(Storage)

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.     

     

    背景(Background)

    Ly6/PLAUR domain containing3 (LYPD-3) is a GPI-linked protein. The structure of LYPD-3 is similar to the urokinasetype plasminogen activator receptor (uPAR). LYPD-3 is a 6 -100 kDa molecule with variable cell type-specific N-O-linked glycosylation, mature human LYPD-3 contains two uPAR/Ly6 domains and a Ser/Thr/Pro-rich (STP) region includes a protease sensitive site . The interaction of LYPD-3 with Laminin 1 and 5 on neighboring cells promotes the adhesion, spreading, and migration of tumor cells. LYPD-3 additionally interacts with Galectin-3 and the anterior gradient proteins AG-2 and AG-3. LYPD-3 overexpression in non-small cell lung cancer is predictive of increased mortality.

     

    电泳(SDS-PAGE)

     

    FOR RESEARCH USE ONLY

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