Recombinant Human Hydroxyacid Oxidase 1 is produced by our E.coli expression system and the target gene encoding Met1-Ile370 is expressed with a Trx, 6His tag at the N-terminus. Accession #: Q9UJM8 Known as: Hydroxyacid Oxidase 1; HAOX1; Glycolate Oxidase; GOX; HAO1; GOX1; HAOX1
制剂(Formulation) Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
质量控制(Quality Control)
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin:
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
运输(Shipping) The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. 保存(Storage)
Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
背景(Background) Hydroxyacid Oxidase 1 (HAO1) is an enzyme that belongs to the FMN-Dependent α-Hydroxy Acid Dehydrogenase family. HAO1 contains 1 FMN Hydroxy Ccid Dehydrogenase domain. HAO1 is expressed primarily in the liver and pancreas. This protein has 2-Hydroxyacid Oxidase activity. Most HAO1 is active on the 2-Carbon substrate Glycolate, but it can also be active on 2-Hydroxy fatty acids, with higher activity towards 2-Hydroxy Palmitate and 2-Hydroxy Octanoate.