- ￥200 - 360
- 近岸蛋白(Novoprotein)
- C031
- 中国
- 2025年11月19日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
Recombinant Human IGF-I
- 规格：
10ug/50ug/500ug/1mg
| 规格： | 10ug | 产品价格： | ￥200.0 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ￥360.0 |
| 规格： | 500ug | 产品价格： | 询价 |
| 规格： | 1mg | 产品价格： | 询价 |
Recombinant Human IGF-I (C031)
产品说明(Description)
Recombinant Human Insulin-like Growth Factor I is produced by our E.coli expression system and the target gene encoding Thr52-Ala118 is expressed.
Accession #: P05019
Known as: Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1
制剂（Formulation）
Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAC,pH 4.5.
质量控制（Quality Control）
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin: Less than 0.05 ng/μg (0.5 EU/μg) as determined by LAL test.
Bioactivity: Measured in a serum-free cell proliferation assay using MCF‑7 human breast cancer cells.
The ED50 for this effect is 20-100 ng/ml.
复溶（Reconstitution）
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存（Storage）
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
背景（Background）
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.
电泳(SDS-PAGE)
参考文献(Reference)
1、A serine protease extracted from Trichosanthes kirilowii induces apoptosis via the PI3K/AKT-mediated mitochondrial pathway in human colorectal adenocarcinoma cells. Song L. et al. Food & function. 2016.
FOR RESEARCH USE ONLY
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