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- 2025年07月14日
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- 详细信息
- 技术资料
- 保存条件：
常温
- 库存：
大量
- 供应商：
联硕生物
- CAS号：
59247-13-1
- 规格：
1瓶
一般描述
Gangliosides are major constituents of neuronal cell membranes and endoplasmic reticulum. They contain a sialated polysaccharide chain linked to ceramide through a β-glycosidic linkage. For classification of gangliosides see Svennerholm, L., et al. (eds.), Structure and Function of Gangliosides, New York, Plenum, 1980.
应用
Trisialoganglioside-GT1b from bovine brain has been used:
in high performance thin layer chromatography (HPTLC)[1]
in membrane GM1 assays[2]
as reference standards for TLC (thin layer chromatography) and as antigens for ELISA (enzyme-linked immunosorbent assay)[3]
生化/生理作用
Ganglioside marker for metastatic brain tumors. Modulates cellular differentiation; prevents glutamate neurotoxicity; inhibits mitogenesis stimulated by lectins such as Con A. Converted to GD1b by bacterial and mammalian sialidases.
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