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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
-20°C 干燥
- 保质期:
12个月
- 英文名:
Amyloid β肽(25-35) (人)
- 供应商:
上海汇谱仪器有限公司
- CAS号:
131602-53-4
- 规格:
1 mg
概述
- 产品名称
Amyloid β肽(25-35) (人) - 描述
Highly toxic amyloid β (25-35) 蛋白片段 - 生物学描述
Highly toxic, synthetic peptide fragment of the amyloid β protein. Displays extremely rapid aggregation and enhanced neurotoxicity. Increases oxidative stress, causes neuronal damage and decreases spatial memory in rats.
- 纯度
> 95%
性能
- 分子量
1060.27 - 化学结构

- 分子式
C45H81N13O14S - CAS编号
131602-53-4 - 序列
GSNKGAIIGLM - 存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. - 溶解度概述
Soluble in water - 处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- 来源
Synthetic
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文献和实验Effects of the β-Amyloid Peptide on Membrane Ion Permeability
Several lines of evidence suggest a role for membrane ion channels in the neurotoxic effects of the β-amyloid peptide (Aβ). This chapter describes the electrophysiological techniques that can be employed to isolate and record specific membrane
, Kawashima S. Effect of amyloid-β-(25~35) on passive avoidance, radial-arm maze learning and choline acetyltranferase activity in the rat[J]. Eur J Pharmacol,2001,412(3):265-72. [8] Pavia J , Alberch J , Alvarez I et al . Repeated intracerebroventricular
A detailed understanding of the biochemical events leading to the proteolytic excision of the β-amyloid peptide (A β) from the amyloid precursor protein (APP) has eluded many researchers. This is largely because the measurement of the various APP
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