生物学描述 H+ /K+-ATPase (proton pump) inhibitor (IC50 = 2.3 µM). S-enantiomer of omeprazole. Attenuates intestinal mucosal barrier damage and can promote healing of gastric lesions in rats. Also inhibits Cytochrome P450 2C19 (CYP2C9), CYP2C19 and CYP3A4 (Ki values are 81.5, 8.6 and 46.6 µM, respectively).
纯度 > 99%
性能
化学名称 6-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt
分子量 367.40
化学结构
分子式 C17H18N3NaO3S
CAS编号 161796-78-7
PubChem识别号 23674541
存放说明 Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
溶解度概述 Soluble in water to 100 mM, in ethanol to 100 mM and in DMSO to 100 mM
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.