YM 202074

概述

• 产品名称
  YM 202074
• 描述
  mGlu₁ antagonist
• 生物学描述
  Potent, selective allosteric mGluR1 antagonist. Binds to an allosteric site of rat mGluR1 with a K_i value of 4.8 nM. Neuroprotective in vivo.
• 纯度
  > 98%

性能

• 化学名称
  N-Cyclohexyl-6-[[(2-methoxyethyl)methylamino]methyl]-N-methylthiazolo[3,2-a]benzimidazole-2-carboxamide sesquifumarate
• 分子量
  414.56
• 化学结构
  
• 分子式
  C₂₂H₃₀N₄O₂S.1.5C₄H₄O₄
• CAS编号
  299900-83-7
• 存放说明
  Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in water to 25 mM (with heating and stirring) and in DMSO to 100 mM
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• 来源

  Synthetic