Pro-myristic acid

概述

• 产品名称
  Pro-myristic acid
• 描述
  Negative control for MiTMAB™ and OcTMAB™
• 生物学描述
  Negative control molecule for use with MiTMAB™ ab120466 and OcTMAB™ ab120467. Pro-myristic acid is an in vitro inhibitor of dynamin I and II, targeting the PH (lipid binding) domain (IC₅₀ = 9.2 µM for inhibition of dynamin I GTPase). Although cell-permeable, it is rapidly broken down by cellular esterases to release intracellular myristic acid, which is not a dynamin inhibitor (IC₅₀ = ≥300 μM for receptor-mediated endocytosis). It can therefore be used as a negative control in cell-based studies with MiTMAB™ and/or OcTMAB™.
• 常规说明
  Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd.

性能

• 化学名称
  2-(Dimethylamino)ethyl tetradecanoate
• 分子量
  299.50
• 化学结构
  
• 分子式
  C₁₈H₃₇NO₂
• CAS编号
  43016-78-0
• PubChem识别号
  96645
• 存放说明
  Store at Room Temperature. The product can be stored for up to 12 months.
• 溶解度概述
  Soluble in DMSO to 25 mM and in ethanol to 100 mM
• 处理

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• SMILES
  CN(C)CCOC(=O)CCCCCCCCCCCCC
• 来源

  Synthetic