Dynamin Inhibitors: Iminodyn™

概述

• 产品名称
  Dynamin Inhibitors: Iminodyn™ Series试剂盒
• 特异性
  Convenient kit containing dynamin inhibitor Iminodyn™ 22 (ab120461; 1 mg) and Iminodyn™ 17 (ab120462; 1 mg) from the Iminodyn chemical series. Iminodyn™ 22 ab120461 targets dynamin at the GTPase Allosteric Site (GAS) domain. It potently inhibits both dynamin I and II in enzymatic assays and is a potent inhibitor of receptor-mediated endocytosis in cells. Iminodyn™ 17 inhibits dynamin I and II in enzymatic assays, but does not affect dynamin mediated endocytosis in cells. It can therefore be used as a negative control for cell based assays.
• 产品概述

  Iminodyn^TM chemical series collection 

  Convenient kit containing dynamin inhibitor Iminodyn™ 22 (ab120461; 1 mg) and Iminodyn™ 17 (ab120462; 1 mg) from the Iminodyn chemical series. Iminodyn™ 22 (ab120461) targets dynamin at the GTPase Allosteric Site (GAS) domain. It potently inhibits both dynamin I and II in enzymatic assays and is a potent inhibitor of receptor-mediated endocytosis in cells. Iminodyn™ 17 inhibits dynamin I and II in enzymatic assays, but does not affect dynamin mediated endocytosis in cells. It can therefore be used as a negative control for cell based assays. 

  Target

  Description 

  GTPase Allosteric Site 

  Iminodyn-22™:  

  Potent, broad spectrum dynamin inhibitor 

  GTPase Allosteric Site 

  Iminodyn-17™:  

  Negative control for Iminodyn-22™ 

• 说明

  Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Iminodyn™ ia a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd.

  Sold under exclusive licence from Children's Medical Research Institute and Newcastle Innovation Ltd. Iminodyn™ is a trademark of Children's Medical Research Institute and Newcastle Innovation Ltd.
• 经测试应用
  适用于: Functional Studiesmore details

性能

• 存放说明
  Store at -20°C. Please refer to protocols.