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- 224579-74-2
- 2025年07月15日
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- 文献和实验
- 技术资料
- 保存条件：
Powder: -80°C, 2 years; -20°C, 1 yearIn solvent: -80°C, 6 months; -20°C, 1 month
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
224579-74-2
- 规格：
1 mg/5 mg/10 mg/25 mg
| 规格： | 1 mg | 产品价格： | ￥500.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1750.0 |
| 规格： | 10 mg | 产品价格： | ￥3200.0 |
| 规格： | 25 mg | 产品价格： | ￥7200.0 |
MLCK inhibitor peptide 18
产品活性：MLCK inhibitor peptide 18 是一种有效的 MLCK 抑制剂，IC50 值为 50 nM，同时较弱抑制 CaM kinase II 的活性。
研究领域：Cytoskeleton | Neuronal Signaling
In Vitro: MLCK inhibitor peptide 18 has a selective effect on peptide substrate utilization by MLCK, does not interfere with kinase activation by CaM, does not have significant inhibitory activity with the closely related CaMPKII, and does not inhibit PKA[1].
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文献和实验Random Mutagenesis of Peptide Aptamers as an Optimization Strategy for Inhibitor Screening
Accumulating work over the past decade has shown that peptide aptamer screening represents a valid strategy for inhibitor identification that can be applied to a variety of different targets. Because of the screening method in cells
are first cleaved with trypsin in water, and subsequently the peptide products are dried and labeled by incubation with trypsin in 18 O-enriched water. One important aspect of this two-step procedure is that peptides, and not proteins, are dried
Identification of Asp Isomerization in Proteins by 18O Labeling and Tandem Mass Spectrometry
to identify the site of modification by LC-MS/MS peptide mapping. Here, we describe an approach to label the Asp residue involved in isomerization at the protein level by hydrolyzing the succinimide intermediate in H 2 18 O. Tryptic digestion of this labeled
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